Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 15/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834990 | 0.93 | ALDH1A1 (0.48) | TRPC5TP53ALDH1A1KCNH2TRPC4 | |
| SCHEMBL18833893 | 0.87 | ALDH1A1 (0.43) | TRPC5TP53ALDH1A1KCNH2TRPC4 | |
| SCHEMBL18834584 | 0.85 | TRPC5 (0.50) | TRPC5TP53KCNH2TRPC4MAPT | |
| SCHEMBL18835068 | 0.82 | ALDH1A1 (0.43) | TRPC5TP53ALDH1A1MAPTADRA2A | |
| SCHEMBL18834209 | 0.81 | ALDH1A1 (0.44) | TP53ALDH1A1MAPTADRA2A | |
| SCHEMBL19374882 | 0.80 | MEN1 (0.44) | TP53ALDH1A1MAPTADRA2A | |
| SCHEMBL18833778 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTADRA2A | |
| SCHEMBL18833894 | 0.76 | KDM4E (0.46) | TRPC5TP53ALDH1A1 | |
| SCHEMBL19374943 | 0.74 | TRPC5 (0.40) | TRPC5TP53ALDH1A1KCNH2TRPC4 | |
| SCHEMBL19375348 | 0.73 | TRPC5 (0.47) | TRPC5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |