Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 6/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834209 | 0.90 | ALDH1A1 (0.44) | ALDH1A1TP53MAPTMEN1KMT2A | |
| SCHEMBL19374882 | 0.89 | MEN1 (0.44) | ALDH1A1TP53MAPTMEN1KMT2A | |
| SCHEMBL18834990 | 0.89 | ALDH1A1 (0.48) | ALDH1A1TP53MAPTMEN1KMT2A | |
| SCHEMBL18834573 | 0.87 | TRPC5 (0.51) | ALDH1A1TP53MAPTTRPC5KCNH2 | |
| SCHEMBL18835068 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TP53MAPTMEN1KMT2A | |
| SCHEMBL19375320 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TP53MAPTMEN1KMT2A | |
| SCHEMBL19375313 | 0.75 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL18835186 | 0.75 | ALDH1A1 (0.38) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL18833721 | 0.74 | MEN1 (0.41) | ALDH1A1TP53MAPTMEN1KMT2A | |
| SCHEMBL18833778 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |