Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16028600 | 0.76 | TRPC5 (0.48) | ADORA3MAPT | |
| SCHEMBL19375294 | 0.73 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL18834315 | 0.71 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL16028545 | 0.68 | TRPC5 (0.57) | MAPT | |
| SCHEMBL18834799 | 0.66 | TRPC4 (0.40) | ADORA2BADORA3ADORA1MAPT | |
| SCHEMBL16027932 | 0.65 | CYP1A2 (0.44) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL18834056 | 0.64 | ALDH1A1 (0.42) | ADORA3ADORA1MEN1KMT2A | |
| SCHEMBL21602541 | 0.64 | TSHR (0.57) | MEN1KMT2A | |
| SCHEMBL16028630 | 0.64 | TRPC5 (0.56) | MAPT | |
| SCHEMBL836600 | 0.61 | CYP1A2 (0.47) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |