Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | FKBP1A | P62942 | 9/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21174516 | 0.81 | RAB9A (0.55) | L3MBTL1FKBP1APOLBSMN1; SMN2USP2 | |
| SCHEMBL1725474 | 0.77 | L3MBTL1 (0.63) | L3MBTL1FKBP1APOLBSMN1; SMN2USP2 | |
| SCHEMBL31434479 | 0.76 | BCHE (0.34) | L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL13221508 | 0.75 | L3MBTL1 (0.59) | L3MBTL1FKBP1APOLBSMN1; SMN2USP2 | |
| SCHEMBL18026620 | 0.75 | L3MBTL1 (0.70) | L3MBTL1FKBP1APOLBSMN1; SMN2USP2 | |
| SCHEMBL5986412 | 0.74 | L3MBTL1 (0.70) | L3MBTL1FKBP1APOLBSMN1; SMN2USP2 | |
| SCHEMBL14538081 | 0.74 | L3MBTL1 (0.70) | L3MBTL1FKBP1APOLBSMN1; SMN2USP2 | |
| SCHEMBL10786869 | 0.73 | L3MBTL1 (0.68) | L3MBTL1FKBP1APOLBSMN1; SMN2USP2 | |
| Hydrochloric Acid SCHEMBL3724641 | 0.73 | L3MBTL1 (0.68) | L3MBTL1FKBP1APOLBSMN1; SMN2USP2 | |
| SCHEMBL14446152 | 0.72 | L3MBTL1 (0.66) | L3MBTL1FKBP1APOLBSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200383959-A1 | THERAPEUTIC AGENT CONTAINING PYRANODIPYRIDINE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-12-10 | — | — | US | disclosed |
| US-20200383959-A1 | THERAPEUTIC AGENT CONTAINING PYRANODIPYRIDINE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-12-10 | — | — | US | disclosed |
| EP-3622954-A1 | THERAPEUTIC AGENT CONTAINING PYRANODIPYRIDINE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2020-03-18 | — | — | EP | disclosed |
| EP-3378863-A1 | PYRANODIPYRIDINE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2018-09-26 | — | — | EP | disclosed |
| US-9738656-B2 | Pyranodipyridine compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-22 | — | — | US | disclosed |
| US-9738656-B2 | Pyranodipyridine compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-22 | — | — | US | disclosed |
| US-9738656-B2 | Pyranodipyridine compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-22 | — | — | US | disclosed |
| US-20170137436-A1 | Pyranodipyridine Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-05-18 | — | — | US | disclosed |
| US-20170137436-A1 | Pyranodipyridine Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-05-18 | — | — | US | disclosed |
| WO-2017082288-A1 | PYRANODIPYRIDINE COMPOUND | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2017-05-18 | — | — | WO | disclosed |
| US-20170137436-A1 | Pyranodipyridine Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200383959-A1 | THERAPEUTIC AGENT CONTAINING PYRANODIPYRIDINE COMPOUND | PSEN1, MAPT, PSEN2 | L3MBTL1 4561/4885FKBP1A 1985/4885POLB 2402/4885 |
| US-20170137436-A1 | Pyranodipyridine Compound | DPYD, CYP2D6, XDH | L3MBTL1 4718/4885FKBP1A 399/4885POLB 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.