Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839563 | 0.82 | ALDH1A1 (0.38) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL23028584 | 0.80 | TDP1 (0.34) | — | |
| SCHEMBL23028585 | 0.79 | NAAA (0.38) | LMNACYP2C19 | |
| SCHEMBL23028664 | 0.78 | — | — | |
| SCHEMBL23028581 | 0.77 | DGKA (0.40) | LMNA | |
| SCHEMBL13266992 | 0.76 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL550435 | 0.76 | CAPN1 (0.35) | — | |
| SCHEMBL13244943 | 0.74 | HRH3 (0.32) | — | |
| SCHEMBL23028658 | 0.74 | ALDH1A1 (0.32) | LMNA | |
| SCHEMBL11283707 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687988-A1 | ANTIBACTERIAL COMPOUND AND USES OF SAME | bioMérieux (FR) | 2020-08-05 | — | — | EP | disclosed |
| WO-2017081615-A1 | 7-OXO -6-(SULFOOXY)- 1,6-DIAZABICYCLO [3.2.1] OCTANE CONTAINING COMPOUNDS AND THEIR USE IN TREATMENT OF BACTERIAL INFECTIONS | WOCKHARDT LIMITED (IN) | 2017-05-18 | — | — | WO | disclosed |