SCHEMBL18844136

SCHEMBL18844136

CCCCC(=O)CC(=O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FAAH O00519 11/20 0.42
CES1 P23141 8/20 0.41
CES2 O00748 4/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HAO1 Q9UJM8 1/20 0.39
PLA2G4A P47712 1/20 0.35
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
EPHX1 P07099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4371316 0.95 FAAH (0.50) FAAHCES1CES2KMT2AMEN1
SCHEMBL18844135 0.93 FAAH (0.52) FAAHCES1CES2KMT2AMEN1
SCHEMBL4373902 0.83 FAAH (0.53) FAAHCES1CES2KMT2AMEN1
SCHEMBL28687905 0.81 FAAH (0.55) FAAHCES1CES2KMT2AMEN1
SCHEMBL13741062 0.81 LMNA (0.41) KMT2AMEN1CYP1A2HSD17B10ALDH1A1
SCHEMBL19320230 0.80 TDP1 (0.38) FAAH
SCHEMBL7252679 0.80 FAAH (0.59) FAAHCES1CES2KMT2AMEN1
SCHEMBL18844137 0.80 KDM4C (0.36) FAAHCES1CES2KMT2AMEN1
SCHEMBL13751379 0.79 THRB (0.31) HAO1
SCHEMBL15826449 0.79 TDP1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170174922-A1 CONDUCTIVE MATERIAL AND SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-06-22 US disclosed
US-20170130070-A1 CONDUCTIVE MATERIAL AND SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-11 US disclosed
US-20170130071-A1 CONDUCTIVE MATERIAL AND SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-05-11 US disclosed