SCHEMBL4373902

SCHEMBL4373902

CCCCCC(=O)CC(=O)C(F)(F)C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FAAH O00519 11/20 0.53
CES1 P23141 10/20 0.52
CES2 O00748 5/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
CYP1A2 P05177 1/20 0.52
HSD17B10 Q99714 1/20 0.52
HAO1 Q9UJM8 1/20 0.48
MAPT P10636 1/20 0.44
AKR1B1 P15121 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28687905 0.98 FAAH (0.55) FAAHCES1CES2KMT2AMEN1
SCHEMBL4371316 0.89 FAAH (0.50) FAAHCES1CES2KMT2AMEN1
SCHEMBL18844135 0.87 FAAH (0.52) FAAHCES1CES2KMT2AMEN1
SCHEMBL19320231 0.86 FAAH (0.39) FAAHCES1CES2KMT2AMEN1
SCHEMBL1347562 0.84 FAAH (0.69) FAAHCES1CES2KMT2AMEN1
SCHEMBL9059827 0.84 FAAH (0.68) FAAHCES1CES2KMT2AMEN1
SCHEMBL18844136 0.83 FAAH (0.42) FAAHCES1CES2KMT2AMEN1
SCHEMBL5466926 0.82 FAAH (0.70) FAAHCES1CES2KMT2AMEN1
SCHEMBL9770770 0.82 FAAH (0.70) FAAHCES1CES2KMT2AMEN1
SCHEMBL11211125 0.82 FAAH (0.70) FAAHCES1CES2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009115644-A1 LANTHANIDE(III) CHELATES COMPRISING BETA-DIKETONES AND CONJUGATES DERIVED THEREOF WALLAC OY (FI) 2009-09-24 WO claimed
EP-1483582-B1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2008-04-16 EP claimed
EP-1483582-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2004-12-08 EP claimed
WO-2003076939-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2003-09-18 WO claimed
US-20030170907-A1 Dissociative fluorescence enhancement assay WALLAC OY (FI) 2003-09-11 US claimed
US-20160258936-A1 METHOD FOR ANALYZING GAS SAMPLES TURUN YLIOPISTO (FI) 2016-09-08 US disclosed
US-20150094234-A1 Method for characterizing and/or determining samples AQSENS OY (FI) 2015-04-02 US disclosed
WO-2009115644-A1 LANTHANIDE(III) CHELATES COMPRISING BETA-DIKETONES AND CONJUGATES DERIVED THEREOF WALLAC OY (FI) 2009-09-24 WO disclosed
US-7381567-B2 Dissociative fluorescence enhancement assay WALLAC OY (FI) 2008-06-03 US disclosed
EP-1483582-B1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2008-04-16 EP disclosed
US-7211440-B2 Dissociative fluorescence enhancement assay WALLAC OY (FI) 2007-05-01 US disclosed
US-20070015284-A1 Dissociative fluorescence enhancement assay HEMMILA ILKKA 2007-01-18 US disclosed
EP-1483582-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2004-12-08 EP disclosed
WO-2003076939-A1 DISSOCIATIVE FLUORESCENCE ENHANCEMENT ASSAY WALLAC OY (FI) 2003-09-18 WO disclosed
US-20030170907-A1 Dissociative fluorescence enhancement assay WALLAC OY (FI) 2003-09-11 US disclosed