Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | POLG | P54098 | 2/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18855468 | 0.88 | POLG (0.59) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL18844327 | 0.88 | POLG (0.59) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL18840494 | 0.88 | POLG (0.59) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL18844322 | 0.88 | POLG (0.59) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL22327467 | 0.87 | POLG (0.53) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL18840575 | 0.85 | P2RY2 (0.40) | POLBP2RY2P2RY4P2RY6POLA1 | |
| SCHEMBL18844356 | 0.84 | DUT (0.47) | P2RY2P2RY4P2RY6 | |
| SCHEMBL18844358 | 0.83 | PRMT5 (0.39) | POLB | |
| SCHEMBL18855439 | 0.82 | POLG (0.57) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL23734249 | 0.80 | POLG (0.57) | POLBPOLGP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137869-A1 | METHODS FOR SYNTHESIZING NUCLEOTIDE ANALOGUES WITH DISULFIDE LINKERS | IsoPlexis Corporation | 2017-05-18 | — | — | US | disclosed |
| US-20170130051-A1 | NUCLEOTIDE ANALOGUES | IsoPlexis Corporation | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137869-A1 | METHODS FOR SYNTHESIZING NUCLEOTIDE ANALOGUES WITH DISULFIDE LINKERS | RNGTT, NT5C3B, DUT | POLB 51/4885POLG 250/4885P2RY2 1196/4885 |
| US-20170130051-A1 | NUCLEOTIDE ANALOGUES | NT5C3B, SAMHD1, DUT | POLB 28/4885POLG 176/4885P2RY2 413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.