Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | FLT3 | P36888 | 2/20 | 0.67 |
| ▸ | CDK2 | P24941 | 2/20 | 0.67 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.67 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.67 |
| ▸ | IDO1 | P14902 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38655498 | 1.00 | YTHDC1 (0.71) | YTHDC1KDM4EFLT3CDK2CCNA2 | |
| SCHEMBL20267042 | 0.83 | SMN1; SMN2 (0.71) | YTHDC1KDM4EFLT3CDK2CCNA2 | |
| SCHEMBL30036108 | 0.83 | YTHDC1 (1.00) | YTHDC1KDM4EFLT3CDK2CCNA2 | |
| SCHEMBL2723267 | 0.83 | YTHDC1 (1.00) | YTHDC1KDM4EFLT3CDK2CCNA2 | |
| SCHEMBL4464788 | 0.82 | KDM4E (0.78) | YTHDC1KDM4EFLT3CDK2CCNA2 | |
| SCHEMBL952028 | 0.81 | SMN1; SMN2 (0.77) | YTHDC1KDM4EFLT3CDK2CCNA2 | |
| SCHEMBL27750743 | 0.80 | KDM4E (0.62) | YTHDC1KDM4EFLT3CDK2CCNA2 | |
| SCHEMBL82761 | 0.80 | KDM4E (0.62) | YTHDC1KDM4EFLT3CDK2CCNA2 | |
| SCHEMBL12193634 | 0.80 | KDM4E (0.53) | YTHDC1KDM4EFLT3CDK2CCNA2 | |
| SCHEMBL951125 | 0.80 | FLT3 (1.00) | YTHDC1KDM4EFLT3CDK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479805-B2 | Indazole hydrazide compound and application thereof | BEIJING BAHEAL CHENGCHUANG PHARMACEUTICAL RESEARCH AND DEVELOPMENT CO., LTD. (CN) | 2025-11-25 | — | — | US | claimed |
| CN-115715776-B | Indazole hydrazide compound and application thereof | 北京大学第一医院 | 2024-10-22 | — | — | CN | claimed |
| CN-118766904-A | Application of indazole hydrazide compound in preparation of medicines for treating fibrosis diseases | 北京大学第一医院 | 2024-10-15 | — | — | CN | claimed |
| CN-118026999-A | Indazole hydrazide compound and application thereof in preparation of medicines for treating cancers | 北京大学第一医院 | 2024-05-14 | — | — | CN | claimed |
| US-20230097420-A1 | INDAZOLE HYDRAZIDE COMPOUND AND APPLICATION THEREOF | PEKING UNIVERSITY FIRST HOSPITAL (CN) | 2023-03-30 | — | — | US | claimed |
| CN-115715776-A | Indazole hydrazide compound and application thereof | 北京大学第一医院 | 2023-02-28 | — | — | CN | claimed |
| CN-112939868-B | Indazole hydrazide compound and application thereof | 北京大学第一医院 | 2022-10-18 | — | — | CN | claimed |
| WO-2022170822-A1 | INDAZOLE HYDRAZIDE COMPOUND AND APPLICATION THEREOF | 北京大学第一医院 | 2022-08-18 | — | — | WO | claimed |
| CN-113101287-A | Application of indazole hydrazide compound in preparation of anti-tumor angiogenesis medicine | 北京大学第一医院 | 2021-07-13 | — | — | CN | claimed |
| CN-112939868-A | Indazole hydrazide compound and application thereof | 北京大学第一医院 | 2021-06-11 | — | — | CN | claimed |
| CN-104356183-B | Compound having anti-tumor effect as well as preparation method and application thereof | 华中科技大学 | 2017-04-26 | — | — | CN | claimed |
| EP-1478357-A2 | TRICYCLIC PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2004-11-24 | — | — | EP | claimed |
| WO-2003070236-A2 | TRICYCLIC PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA S.P.A. (IT) | 2003-08-28 | — | — | WO | claimed |
| CN-122036615-A | Indazole hydrazide compound and preparation method and application thereof | 南京农业大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-122036615-A | Indazole hydrazide compound and preparation method and application thereof | 南京农业大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-122036615-A | Indazole hydrazide compound and preparation method and application thereof | 南京农业大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-101054375-A | Compound capable of inhibiting tubercle bacillus growth and application thereof | UNIV FUDAN (CN) | 2007-10-17 | — | — | CN | disclosed |
| EP-1478357-A2 | TRICYCLIC PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003070236-A2 | TRICYCLIC PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA S.P.A. (IT) | 2003-08-28 | — | — | WO | disclosed |
| US-3956312-A | ANTISECRETORY AGENT | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479805-B2 | Indazole hydrazide compound and application thereof | ITGB3, AR, HDAC3 | YTHDC1 4663/4885KDM4E 755/4885FLT3 607/4885 |
| US-20230097420-A1 | INDAZOLE HYDRAZIDE COMPOUND AND APPLICATION THEREOF | ITGB3, AR, HDAC3 | YTHDC1 4663/4885KDM4E 755/4885FLT3 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.