SCHEMBL18852012

SCHEMBL18852012

O=c1[nH]c2c3cc(Br)ccc3oc2c2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2B P67870 13/20 0.51
PIM1 P11309 13/20 0.51
CSNK2A2 P19784 10/20 0.51
PIM3 Q86V86 9/20 0.51
PIM2 Q9P1W9 9/20 0.51
CDC7 O00311 5/20 0.51
CSNK2A1 P68400 5/20 0.51
CSNK2A3 Q8NEV1 1/20 0.51
GABRP O00591 2/20 0.44
GABRD O14764 2/20 0.44
GABRA1 P14867 2/20 0.44
GABRB1 P18505 2/20 0.44
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44
GABRA5 P31644 2/20 0.44
GABRA3 P34903 2/20 0.44
GABRA2 P47869 2/20 0.44
GABRB2 P47870 2/20 0.44
GABRA4 P48169 2/20 0.44
GABRE P78334 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5323077 0.82 ALDH1A1 (0.56) CSNK2BPIM1CSNK2A2PIM3PIM2
SCHEMBL4078024 0.82 MAOA (0.53) CSNK2BPIM1CSNK2A2PIM3PIM2
SCHEMBL18852011 0.82 PIM1 (0.47) CSNK2BPIM1CSNK2A2PIM3PIM2
SCHEMBL12105403 0.81 AR (0.46) CSNK2BPIM1CSNK2A2PIM3PIM2
SCHEMBL4072818 0.79 MAOA (0.56) CSNK2BPIM1CSNK2A2PIM3PIM2
SCHEMBL1854409 0.79 PIM1 (0.54) CSNK2BPIM1CSNK2A2PIM3PIM2
SCHEMBL12105373 0.78 AR (0.52) CSNK2BPIM1CSNK2A2PIM3PIM2
SCHEMBL1854093 0.77 CSNK2B (0.51) CSNK2BPIM1CSNK2A2PIM3PIM2
SCHEMBL28628974 0.76 AR (0.49) CSNK2BPIM1CSNK2A2PIM3PIM2
SCHEMBL13377623 0.75 AR (0.55) CSNK2BPIM1CSNK2A2PIM3CDC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017078182-A1 BENZIMIDAZOLE FUSED HETEROARYLS IDEMITSU KOSAN CO., LTD. (JP) 2017-05-11 WO disclosed