Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | NR2E3 | Q9Y5X4 | 3/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028590 | 0.88 | ALDH1A1 (0.47) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL5323077 | 0.82 | ALDH1A1 (0.56) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL18852012 | 0.82 | CSNK2B (0.51) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL4078024 | 0.82 | MAOA (0.53) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL4072818 | 0.82 | MAOA (0.56) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL23351567 | 0.78 | BCHE (0.46) | ALDH1A1KDM4EHTTLMNAPPARG | |
| SCHEMBL28646096 | 0.76 | ALDH1A1 (0.49) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL13377717 | 0.75 | MEN1 (0.58) | ALDH1A1KDM4ELMNARXFP1MAPT | |
| SCHEMBL10223077 | 0.75 | NOS1 (0.45) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL24558366 | 0.73 | KIF11 (0.54) | ALDH1A1KDM4EHTTPPARGNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017078182-A1 | BENZIMIDAZOLE FUSED HETEROARYLS | IDEMITSU KOSAN CO., LTD. (JP) | 2017-05-11 | — | — | WO | disclosed |