Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18856284 | 0.95 | CA2 (0.38) | FAAHCNR1CNR2CA1LMNA | |
| SCHEMBL609475 | 0.85 | CTSK (0.41) | FAAHCA1ABCB1LMNATRPV1 | |
| SCHEMBL18856281 | 0.84 | LMNA (0.50) | FAAHCNR1CNR2CA1ABCB1 | |
| SCHEMBL18856345 | 0.84 | LMNA (0.50) | FAAHCNR1CNR2CA1ABCB1 | |
| SCHEMBL18924867 | 0.84 | FAAH (0.56) | FAAHCNR1CNR2CA1LMNA | |
| SCHEMBL18856273 | 0.84 | FAAH (0.56) | FAAHCNR1CNR2CA1LMNA | |
| SCHEMBL19018698 | 0.81 | MAPT (0.33) | MAPT | |
| SCHEMBL5873220 | 0.79 | FAAH (0.58) | FAAHCNR1CNR2CA1LMNA | |
| SCHEMBL18856347 | 0.78 | FAAH (0.43) | FAAHCNR1CNR2ABCB1LMNA | |
| SCHEMBL18856274 | 0.78 | FAAH (0.40) | FAAHCNR1CNR2CA1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650341-B2 | Process for synthesizing oxidized lactam compounds | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-05-16 | — | — | US | disclosed |