⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257806 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL609663 | 0.71 | — | — | |
| SCHEMBL28237964 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL250276 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL2465792 | 0.67 | ALDH1A1 (0.30) | — | |
| SCHEMBL22616909 | 0.65 | LMNA (0.37) | — | |
| SCHEMBL3197195 | 0.65 | — | — | |
| SCHEMBL2347991 | 0.64 | CA12 (0.32) | — | |
| SCHEMBL3359802 | 0.63 | — | — | |
| SCHEMBL7644031 | 0.62 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150342165-A1 | HUMANIZED MOUSE AND METHODS OF USING THE SAME | CITY OF HOPE | 2015-12-03 | — | — | US | claimed |
| EP-2538944-B1 | COMPOUND FOR TREATING BRAIN CANCER | NIIKI PHARMA INC (US) | 2014-10-22 | — | — | EP | claimed |
| US-20120040914-A1 | ENHANCING EFFECTIVENESS OF GLIAL CANCER THERAPIES | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2012-02-16 | — | — | US | claimed |
| US-7858659-B2 | Redox therapy for tumors | HOFFMAN ARNOLD | 2010-12-28 | — | — | US | claimed |
| US-20260130855-A1 | GAMMA POLYGLUTAMATED ANTIFOLATES AND USES THEREOF | L E A F HOLDINGS GROUP LLC (US) | 2026-05-14 | — | — | US | disclosed |
| US-12622874-B2 | Trans-crocetin compositions and treatment regimens | L.E.A.F. HOLDINGS GROUP LLC (US) | 2026-05-12 | — | — | US | disclosed |
| US-20260103694-A1 | TARGETED GENE INSERTION FOR IMPROVED IMMUNE CELLS THERAPY | CELLECTIS (FR) | 2026-04-16 | — | — | US | disclosed |
| US-20260053806-A1 | GAMMA POLYGLUTAMATED METHOTREXATE AND USES THEREOF | L E A F HOLDINGS GROUP LLC (US) | 2026-02-26 | — | — | US | disclosed |
| US-20260048054-A1 | ALPHA POLYGLUTAMATED TETRAHYDROFOLATES AND USES THEREOF | L E A F HOLDINGS GROUP LLC (US) | 2026-02-19 | — | — | US | disclosed |
| US-20260014079-A1 | CAROTENOID COMPOSITIONS AND USES THEREOF | L E A F HOLDINGS GROUP LLC (US) | 2026-01-15 | — | — | US | disclosed |
| EP-3706801-B1 | PLATINUM COMPLEXES AND USES THEREOF | L E A F HOLDINGS GROUP LLC (US) | 2026-01-14 | — | — | EP | disclosed |
| EP-4667017-A2 | CAROTENOID COMPOSITIONS AND USES THEREOF | L.E.A.F Holdings Group LLC (US) | 2025-12-24 | — | — | EP | disclosed |
| US-6300458-B1 | High molecular weight polymers and copolymers of BHMDO for biomedical application | VANDENBERG, DAVID J | 2001-10-09 | — | — | US | disclosed |
| US-5538970-A | Treatment of cancer with imidazo-1,2-pyridazin compounds | GLAXO WELLCOME INC. (US) | 1996-07-23 | — | — | US | disclosed |
| US-5447956-A | Anticarcinogenic agents | BURROUGHS WELLCOME CO. (US) | 1995-09-05 | — | — | US | disclosed |
| US-5380759-A | Methyl N-[6-(3,4,5-trimethoxybenzloxy)imidazo[1,2-b]pyridazin-2-zyl]carbamate used to treat leukemia | BURROUGHS WELLCOME CO. (US) | 1995-01-10 | — | — | US | disclosed |
| US-5371219-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0305093-B1 | Imidazo(1,2-b)pyridazine derivatives | WELLCOME FOUND (GB) | 1994-04-06 | — | — | EP | disclosed |
| US-5091531-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0305093-A1 | Imidazo(1,2-b)pyridazine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-03-01 | — | — | EP | disclosed |