SCHEMBL2465792

SCHEMBL2465792

CC(Cl)N(C(=O)NN=O)C(C)Cl

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10344284 0.73 TSHR (0.37) ALDH1A1
SCHEMBL609663 0.67
SCHEMBL188597 0.67
SCHEMBL10933886 0.67 LMNA (0.33) ALDH1A1
SCHEMBL7960409 0.64 ALDH1A1 (0.30) ALDH1A1
SCHEMBL7423100 0.64 LMNA (0.37) ALDH1A1
SCHEMBL19641937 0.62 ALOX5 (0.39)
SCHEMBL22616909 0.62 LMNA (0.37) ALDH1A1
SCHEMBL2465797 0.61 ALDH1A1 (0.32) ALDH1A1
SCHEMBL17791665 0.60 LMNA (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4777515-B2 2011-09-21 JP claimed
US-7498332-B2 Therapy for cerebral vasospasm DUKE UNIVERSITY (US) 2009-03-03 US claimed
EP-1124950-B1 Morpholino based p53 antisense oligonucleotide, and uses thereof AVI BIOPHARMA INC (US) 2006-07-12 EP claimed
WO-2005049811-A1 RADIOMINETIC METHOD OF PRODUCING A RODENT XENOGRAFT MODEL HAVING HUMANIZED MAMMARY FAT PAD WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2005-06-02 WO claimed
US-20020160001-A1 Therapy for cerebral vasospasm DUKE UNIVERSITY 2002-10-31 US claimed
JP-2002528464-A 2002-09-03 JP claimed
US-6365577-B1 p53 antisense agent and method AVI BIOPHARMA, INC. 2002-04-02 US claimed
EP-1124950-A2 p53 ANTISENSE AGENT AND METHOD Avi Biopharma, Inc. (US) 2001-08-22 EP claimed
WO-2000024885-A2 p53 MORPHOLINO-BASED ANTISENSE AVI BIOPHARMA, INC. (US) 2000-05-04 WO claimed
US-7498332-B2 Therapy for cerebral vasospasm DUKE UNIVERSITY (US) 2009-03-03 US disclosed
EP-1667727-B1 POLYAMINE-METAL CHELATOR CONJUGATES UNIV FLORIDA (US) 2008-07-09 EP disclosed
US-20060211773-A1 Polyamine-metal chelator conjugates UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2006-09-21 US disclosed
EP-1124950-B1 Morpholino based p53 antisense oligonucleotide, and uses thereof AVI BIOPHARMA INC (US) 2006-07-12 EP disclosed
EP-1667727-A2 POLYAMINE-METAL CHELATOR CONJUGATES University of Florida Research Foundation, Inc. (US) 2006-06-14 EP disclosed
US-6365577-B1 p53 antisense agent and method AVI BIOPHARMA, INC. 2002-04-02 US disclosed
EP-1124950-A2 p53 ANTISENSE AGENT AND METHOD Avi Biopharma, Inc. (US) 2001-08-22 EP disclosed
WO-2000024885-A2 p53 MORPHOLINO-BASED ANTISENSE AVI BIOPHARMA, INC. (US) 2000-05-04 WO disclosed
US-5736129-A Flow cytometric pharmacosensitivity assay and method of cancer treatment SHAKER CORPORATION, A DELAWARE CORPORATION 1998-04-07 US disclosed
WO-1997019189-A1 FLOW CYTOMETRIC PHARMACOSENSITIVITY ASSAY AND METHOD OF CANCER TREATMENT MEDENICA RAJKO D (US) 1997-05-29 WO disclosed
EP-0331505-A1 A method for purification of liposome composition Takeda Chemical Industries, Ltd. (JP) 1989-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060211773-A1 Polyamine-metal chelator conjugates SLC40A1, SLC7A1, CATSPER1 ALDH1A1 1917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.