⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27111947 | 0.74 | — | — | |
| SCHEMBL5691581 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL2599790 | 0.72 | CTH (0.36) | — | |
| SCHEMBL188597 | 0.71 | — | — | |
| SCHEMBL22616909 | 0.70 | LMNA (0.37) | — | |
| SCHEMBL25874849 | 0.70 | — | — | |
| SCHEMBL6987286 | 0.70 | ALDH1A1 (0.44) | — | |
| SCHEMBL5470221 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL7644031 | 0.67 | TSHR (0.35) | — | |
| SCHEMBL2465792 | 0.67 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3779446-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE USING SALMONELLA T3SS EFFECTOR PROTEIN (SIPA) | University of Massachusetts (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20210023169-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE USING SALMONELLA T3SS EFFECTOR PROTEIN (SipA) | UNIVERSITY OF MASSACHUSETTS | 2021-01-28 | — | — | US | disclosed |
| US-10835575-B2 | Compositions and methods for treating disease using Salmonella T3SS effector protein (SipA) | UNIVERSITY OF MASSACHUSETTS (US) | 2020-11-17 | — | — | US | disclosed |
| EP-3084445-B1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE USING SALMONELLA T3SS EFFECTOR PROTEIN (SIPA) | UNIV MASSACHUSETTS (US) | 2020-10-28 | — | — | EP | disclosed |
| US-20190240286-A1 | Compositions and Methods for Treating Disease Using Salmonella T3SS Effector Protein (SipA) | UNIVERSITY OF MASSACHUSETTS | 2019-08-08 | — | — | US | disclosed |
| US-10201589-B2 | Compositions and methods for treating disease using Salmonella T3SS effector protein (SipA) | UNIVERSITY OF MASSACHUSETTS (US) | 2019-02-12 | — | — | US | disclosed |
| US-20170035837-A1 | Compositions and Methods for Treating Disease Using Salmonella T3SS Effector Protein (SipA) | UNIVERSITY OF MASSACHUSETTS (US) | 2017-02-09 | — | — | US | disclosed |
| EP-3084445-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE USING SALMONELLA T3SS EFFECTOR PROTEIN (SIPA) | University of Massachusetts (US) | 2016-10-26 | — | — | EP | disclosed |
| US-9353218-B2 | Kit for multifunctional compounds forming crosslinked biomaterials | ANGIOTECH PHARMACEUTICALS, INC. | 2016-05-31 | — | — | US | disclosed |
| US-9326934-B2 | Drug delivery from rapid gelling polymer composition | ANGIOTECH INTERNATIONAL AG | 2016-05-03 | — | — | US | disclosed |
| US-20040063929-A1 | Beta-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| US-20030216758-A1 | Coated surgical patches | ANGIOTECH PHARMACEUTICALS, INC. (CA) | 2003-11-20 | — | — | US | disclosed |
| EP-1362855-A1 | BETA-LACTAM COMPOUNDS, PROCESS FOR REPODUCING THE SAME AND SERUM CHOLESTEROL-LOWERING AGENTS CONTAINING THE SAME | Kotobuki Pharmaceutical Co., Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-20030144570-A1 | Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors | ANGIOTECH PHARMACEUTICALS, INC. (CA) | 2003-07-31 | — | — | US | disclosed |
| WO-2003059408-A2 | SURGICAL PATCHES WITH A BIOLOGICAL ACTIVE AGENT | ANGIOTECH INTERNATIONAL AG (CH) | 2003-07-24 | — | — | WO | disclosed |
| EP-1235598-A2 | COMPOSITIONS OF A COMBINATION OF RADIOACTIVE THERAPY AND CELL-CYCLE INHIBITORS | Angiotech Pharmaceuticals, Inc. (CA) | 2002-09-04 | — | — | EP | disclosed |
| US-20020055666-A1 | Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors | ANGIOTECH INTERNATIONAL AG (CH) | 2002-05-09 | — | — | US | disclosed |
| WO-2001036007-A2 | COMPOSITIONS OF A COMBINATION OF RADIOACTIVE THERAPY AND CELL-CYCLE INHIBITORS | ANGIOTECH PHARMACEUTICALS, INC. (CA) | 2001-05-25 | — | — | WO | disclosed |
| US-5308829-A | Substituted with pyrimidine ring | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0561319-A1 | Benzofuranyl substituted uracil derivatives, and their production and use as herbicides | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |