Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886120 | 0.81 | POLB (0.53) | L3MBTL1HTTMAPTTP53CYP3A4 | |
| SCHEMBL1879427 | 0.77 | HDAC3 (0.56) | L3MBTL1HTTMAPTKDM4ETP53 | |
| SCHEMBL3079822 | 0.76 | CNR1 (0.38) | SMPD1 | |
| SCHEMBL3072804 | 0.72 | HTT (0.55) | L3MBTL1HTTMAPTKDM4ERAB9A | |
| SCHEMBL1948576 | 0.72 | MEN1 (0.46) | L3MBTL1MAPTKDM4ETP53CYP3A4 | |
| SCHEMBL688943 | 0.71 | MAPT (0.47) | L3MBTL1MAPTKDM4ECYP3A4TSHR | |
| SCHEMBL1947888 | 0.70 | LMNA (0.41) | L3MBTL1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1947907 | 0.70 | MAPT (0.40) | L3MBTL1HTTMAPTKDM4ETP53 | |
| SCHEMBL8085869 | 0.70 | SMPD1 (0.68) | SMPD1TP53HDAC3HDAC2 | |
| SCHEMBL31650388 | 0.70 | ALDH1A1 (0.60) | L3MBTL1HTTMAPTTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939688-B2 | Reacting N-alkylcarboxamides or ammonium salts of carboxylic acids in the presence of alkylamines or ammonium salts of in presence of 2,4,6-substituted 1,3,5,2,4,6-trioxatriphosphinane 2,4,6-trioxide and/or a base | ARCHIMICA GMBH (DE) | 2011-05-10 | — | — | US | disclosed |
| US-20080242884-A1 | Process for Preparing Nitriles by Elimination Reactions | EUTICALS GMBH (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242884-A1 | Process for Preparing Nitriles by Elimination Reactions | CBR1, CBR3, PHOSPHO1 | SMPD1 3858/4885L3MBTL1 4371/4885HTT 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.