Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.55 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22722176 | 0.95 | REN (0.58) | RENSLC15A2ERAP2ERAP1LNPEP | |
| SCHEMBL18857604 | 0.86 | SLC6A5 (0.50) | RENSLC15A2ERAP2ERAP1LNPEP | |
| SCHEMBL18862465 | 0.86 | SLC15A2 (0.53) | RENSLC15A2ERAP2ERAP1LNPEP | |
| SCHEMBL18862366 | 0.85 | GHSR (0.60) | REN | |
| SCHEMBL27624890 | 0.85 | SLC15A2 (0.61) | RENSLC15A2ERAP2ERAP1LNPEP | |
| SCHEMBL19051548 | 0.84 | REN (0.57) | RENSLC15A2ERAP2ERAP1LNPEP | |
| SCHEMBL19051549 | 0.83 | SLC15A2 (0.56) | RENSLC15A2HRH1SLC6A5 | |
| SCHEMBL18862360 | 0.82 | REN (0.52) | RENSLC15A2ERAP2ERAP1LNPEP | |
| SCHEMBL18862464 | 0.82 | GHSR (0.62) | REN | |
| SCHEMBL18862042 | 0.81 | REN (0.56) | RENSLC15A2ERAP2ERAP1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137801-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-05-18 | — | — | US | disclosed |