SCHEMBL18868049

SCHEMBL18868049

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4cc(-c5ccccc5)c5oc6ccccc6c5c43)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.38
▸ ALDH1A1 P00352 5/20 0.38
▸ TSHR P16473 4/20 0.38
▸ KDM4E B2RXH2 3/20 0.38
▸ POLB P06746 2/20 0.38
▸ LMNA P02545 4/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.37
▸ HPGD P15428 1/20 0.35
▸ CDC14B O60729 1/20 0.35
▸ CDC14A Q9UNH5 1/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ USP2 O75604 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ CYP1A2 P05177 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27324269 0.98 MAPT (0.37) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL27324250 0.91 MAPT (0.37) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18561399 0.91 MAPT (0.37) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL21018299 0.90 CDC14B (0.34) MAPTALDH1A1KDM4EMAPK1NPSR1
SCHEMBL20175682 0.88 MAPT (0.33) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18594139 0.87 MAPT (0.37) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL21018292 0.87 MAPT (0.41) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18594053 0.86 MAPT (0.37) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL21017487 0.86 MAPT (0.36) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL21017895 0.86 MAPT (0.36) MAPTALDH1A1TSHRKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11569452-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-01-31 — — US disclosed
US-20200194681-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-06-18 — — US disclosed
US-10615348-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-07 — — US disclosed
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-12-26 — — US disclosed
US-20190157603-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-23 — — US disclosed
US-20170141323-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-05-18 — — US disclosed
US-20170141323-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11569452-B2 Organic light-emitting device CRY1, TRPA1, CRY2 MAPT 126/4885ALDH1A1 268/4885TSHR 3287/4885
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, LIN28A, OR51E2 MAPT 1108/4885ALDH1A1 1016/4885TSHR 4356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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