Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567303 | 0.78 | KISS1R (0.46) | KISS1RHTR2AHRH1EPHX1 | |
| SCHEMBL11393539 | 0.76 | — | — | |
| SCHEMBL3068808 | 0.76 | ALDH1A1 (0.34) | — | |
| SCHEMBL25774534 | 0.74 | GABBR2 (0.32) | — | |
| SCHEMBL19578139 | 0.72 | KISS1R (0.40) | KISS1RHTR2AHRH1EPHX1 | |
| SCHEMBL19504757 | 0.72 | KISS1R (0.40) | KISS1RHTR2AHRH1EPHX1 | |
| SCHEMBL11973508 | 0.72 | SPHK1 (0.42) | — | |
| SCHEMBL2116722 | 0.72 | ALDH1A1 (0.34) | — | |
| SCHEMBL21365187 | 0.71 | KISS1R (0.42) | KISS1RHTR2AHRH1EPHX1 | |
| SCHEMBL21276538 | 0.71 | EPHX1 (0.39) | KISS1RHTR2AHRH1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3797775-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | Novartis AG (CH) | 2021-03-31 | — | — | EP | disclosed |
| EP-3167886-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | SARcode Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |