Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PYGB | P11216 | 1/20 | 0.32 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.31 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.31 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.31 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13039997 | 0.84 | — | — | |
| SCHEMBL9912325 | 0.82 | AMY2A (0.39) | AMY1AALDH1A1TSHRLMNATDP1 | |
| SCHEMBL11892843 | 0.82 | AMY2A (0.39) | AMY1AALDH1A1TSHRLMNATDP1 | |
| SCHEMBL23188294 | 0.80 | LGALS8 (0.31) | LGALS8 | |
| SCHEMBL13205044 | 0.80 | AMY1A (0.38) | AMY1AALDH1A1TSHRLMNATDP1 | |
| SCHEMBL22423226 | 0.78 | LGALS8 (0.45) | AMY1APYGBLGALS1LGALS3LGALS8 | |
| SCHEMBL9914030 | 0.78 | LGALS8 (0.45) | AMY1APYGBLGALS1LGALS3LGALS8 | |
| SCHEMBL21083400 | 0.78 | LGALS8 (0.45) | AMY1APYGBLGALS1LGALS3LGALS8 | |
| SCHEMBL21077738 | 0.78 | LGALS8 (0.45) | AMY1APYGBLGALS1LGALS3LGALS8 | |
| SCHEMBL23603150 | 0.78 | LGALS8 (0.45) | AMY1APYGBLGALS1LGALS3LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137815-A1 | NOVEL SINGLE CHEMICAL ENTITIES AND METHODS FOR DELIVERY OF OLIGONUCLEOTIDES | SIRNA THERAPEUTICS INC (US) | 2017-05-18 | — | — | US | disclosed |