SCHEMBL23188294

SCHEMBL23188294

COC1C(C)OC(CO)C1OP

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 2/20 0.31
▸ AMY2A P04746 1/20 0.30
▸ OGA O60502 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24709746 0.90 LGALS8 (0.33) LGALS8AMY2AOGA
SCHEMBL17058711 0.90 LGALS8 (0.33) LGALS8AMY2AOGA
SCHEMBL24709744 0.90 LGALS8 (0.33) LGALS8AMY2AOGA
SCHEMBL23378918 0.90 LGALS8 (0.33) LGALS8AMY2AOGA
SCHEMBL13864486 0.90 LGALS8 (0.33) LGALS8AMY2AOGA
SCHEMBL18868622 0.80 AMY1A (0.38) LGALS8
SCHEMBL13625826 0.79 — —
SCHEMBL20845380 0.78 L3MBTL1 (0.31) —
SCHEMBL12899675 0.78 LGALS8 (0.45) LGALS8OGA
SCHEMBL12141264 0.78 LGALS8 (0.45) LGALS8OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210145852-A1 Combination Therapies for Treating Muscular Dystrophy SAREPTA THERAPEUTICS INC (US) 2021-05-20 — — US disclosed
US-20210102205-A1 EXON SKIPPING OLIGOMERS AND OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY SAREPTA THERAPEUTICS, INC. (US) 2021-04-08 — — US disclosed
US-9517977-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2016-12-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210145852-A1 Combination Therapies for Treating Muscular Dystrophy UTRN, MBNL1, TNNC1 LGALS8 1101/4885AMY2A 3161/4885OGA 4276/4885
US-20210102205-A1 EXON SKIPPING OLIGOMERS AND OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY UTRN, RBM17, UPF1 LGALS8 2500/4885AMY2A 2961/4885OGA 1610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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