Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293678 | 0.84 | ADORA3 (0.46) | KDM4EALDH1A1HPGDPARP1PTGS1 | |
| SCHEMBL18832291 | 0.80 | KDM4E (0.51) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL18870687 | 0.76 | HTT (0.49) | MEN1KMT2APKMKDM4EALDH1A1 | |
| SCHEMBL4058506 | 0.69 | ADORA3 (0.59) | KMT2AKDM4EALDH1A1HPGDPARP1 | |
| SCHEMBL30677327 | 0.68 | XDH (0.54) | MEN1KMT2AALDH1A1PTGS1PTGS2 | |
| SCHEMBL1070489 | 0.66 | PDE8B (0.57) | KDM4EALDH1A1HPGDMAPTCCNE2 | |
| SCHEMBL3821565 | 0.66 | YTHDC1 (0.57) | MEN1KMT2AHPGDCCNE2CCNE1 | |
| SCHEMBL5440560 | 0.65 | CDK2 (0.43) | MAPTSMN1; SMN2CCNE2CCNE1CDK2 | |
| SCHEMBL30677266 | 0.65 | CYP1A2 (0.52) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12325734 | 0.65 | KDM4E (0.65) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168224-A1 | ORGANOZINC COMPOSITION | Ludwig-Maximilians-Universität München (DE) | 2017-05-17 | — | — | EP | disclosed |