Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 8/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293678 | 0.81 | ADORA3 (0.46) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL18870394 | 0.80 | MEN1 (0.47) | KDM4EALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL5914299 | 0.69 | ALDH1A1 (0.54) | KDM4EALDH1A1SMN1; SMN2TP53RAB9A | |
| SCHEMBL5914423 | 0.68 | ALDH1A1 (0.56) | KDM4EALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL4058506 | 0.67 | ADORA3 (0.59) | KDM4EALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL3821565 | 0.66 | YTHDC1 (0.57) | L3MBTL1HPGDMEN1KMT2ACCNE2 | |
| SCHEMBL1070489 | 0.66 | PDE8B (0.57) | KDM4EALDH1A1TP53MAPTCNR2 | |
| SCHEMBL30677327 | 0.65 | XDH (0.54) | ALDH1A1SMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL17262807 | 0.64 | HDAC1 (0.50) | KDM4EALDH1A1TP53MAPTLMNA | |
| SCHEMBL5161254 | 0.63 | CCNE2 (0.52) | KDM4EMAPTGAACCNE2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168224-A1 | ORGANOZINC COMPOSITION | Ludwig-Maximilians-Universität München (DE) | 2017-05-17 | — | — | EP | disclosed |
| EP-3168224-A1 | ORGANOZINC COMPOSITION | Ludwig-Maximilians-Universität München (DE) | 2017-05-17 | — | — | EP | disclosed |