SCHEMBL18873473

SCHEMBL18873473

C=C1C=CC(=S)c2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
CDC25B P30305 1/20 0.31
AKT1 P31749 1/20 0.31
SNCA P37840 1/20 0.31
MAP2K1 Q02750 1/20 0.31
PIN1 Q13526 1/20 0.31
EHMT2 Q96KQ7 1/20 0.31
NSD1 Q96L73 1/20 0.31
EHMT1 Q9H9B1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4762319 0.84 IDO1 (0.40) IDO1MAOAMAOBCDC25BAKT1
SCHEMBL10343652 0.70 IDO1 (0.70) IDO1MAOAMAOBCDC25BAKT1
SCHEMBL30536055 0.70 IDO1 (0.70) IDO1MAOAMAOBCDC25BAKT1
SCHEMBL29625958 0.69 LMNA (0.46) IDO1MAOAMAOBCDC25BAKT1
SCHEMBL867585 0.69 LMNA (0.46) IDO1MAOAMAOBCDC25BAKT1
SCHEMBL18873081 0.67 LMNA (0.40) IDO1
SCHEMBL18873569 0.67 LMNA (0.40) IDO1
SCHEMBL15542936 0.67 LMNA (0.44) IDO1MAOAMAOBCDC25BAKT1
SCHEMBL9784286 0.60 LMNA (0.43) IDO1MAOAMAOBCDC25BAKT1
SCHEMBL18873083 0.60 DCUN1D1 (0.34) MAOACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11046889-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2021-06-29 US disclosed
US-10919870-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2021-02-16 US disclosed
US-10649124-B2 Composition including compound having mesogenic group, polymer and optically anisotropic body obtained by polymerizing polymerizable composition, and phase difference film DIC CORPORATION (JP) 2020-05-12 US disclosed
US-20190025490-A1 COMPOSITION INCLUDING COMPOUND HAVING MESOGENIC GROUP, POLYMER AND OPTICALLY ANISOTROPIC BODY OBTAINED BY POLYMERIZING POLYMERIZABLE COMPOSITION, AND PHASE DIFFERENCE FILM DIC CORPORATION (JP) 2019-01-24 US disclosed
US-20180022716-A1 POLYMERIZABLE COMPOUND AND OPTICAL ISOMER DIC CORPORATION (JP) 2018-01-25 US disclosed
US-20180022716-A1 POLYMERIZABLE COMPOUND AND OPTICAL ISOMER DIC CORPORATION (JP) 2018-01-25 US disclosed
WO-2017079867-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919870-B2 Polymerizable compound and optically anisotropic body ZYX, ZW10, DPY30 IDO1 1608/4885MAOA 2155/4885MAOB 1974/4885
US-20180022716-A1 POLYMERIZABLE COMPOUND AND OPTICAL ISOMER SMC4, MAP1LC3C, ZW10 IDO1 2590/4885MAOA 2024/4885MAOB 2580/4885
US-11046889-B2 Polymerizable compound and optically anisotropic body OCIAD1, RCC1, OCIAD2 IDO1 1412/4885MAOA 543/4885MAOB 667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.