Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18873805 | 1.00 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL6727555 | 0.83 | L3MBTL1 (0.35) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL18874243 | 0.83 | L3MBTL1 (0.35) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL18873885 | 0.80 | L3MBTL1 (0.33) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL6727443 | 0.80 | L3MBTL1 (0.33) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL6727746 | 0.80 | L3MBTL1 (0.33) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL9110635 | 0.80 | L3MBTL1 (0.33) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL18873778 | 0.80 | L3MBTL1 (0.33) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL6727345 | 0.74 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1BRD4LMNA | |
| SCHEMBL18874119 | 0.74 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1BRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173755-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2017-05-17 | — | — | EP | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8835657-B2 | Cyclopentanedione compounds and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2014-09-16 | — | — | US | disclosed |
| US-8835657-B2 | Cyclopentanedione compounds and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2014-09-16 | — | — | US | disclosed |
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| WO-2010127797-A2 | CYCLOPENTANEDIONE COMPOUNDS AND THEIR USE AS INSECTICIDES, ACARICIDES AND/OR FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-11-11 | — | — | WO | disclosed |
| WO-2009019015-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | CYP51A1, CYP1B1, CBR3 | ALDH1A1 164/4885MEN1 1823/4885KMT2A 4194/4885 |
| US-20120142529-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | ALDH1A1 14/4885MEN1 4280/4885KMT2A 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.