Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | GHSR | Q92847 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192173 | 0.85 | GFER (0.74) | KMT2AALDH1A1MEN1GFERTP53 | |
| SCHEMBL23657719 | 0.81 | RAB9A (0.63) | KMT2AALDH1A1MEN1GFERTP53 | |
| SCHEMBL12585052 | 0.81 | MAPK1 (0.79) | KMT2AALDH1A1PTGS2TP53MAPK1 | |
| SCHEMBL4422171 | 0.80 | GAA (0.72) | KMT2AALDH1A1MEN1GFERTP53 | |
| SCHEMBL31610836 | 0.80 | GAA (0.76) | ALDH1A1GFERTP53GAAALOX15 | |
| SCHEMBL13501815 | 0.80 | ALDH1A1 (0.84) | ALDH1A1PTGS2TP53MAPK1SMN1; SMN2 | |
| SCHEMBL7551575 | 0.79 | GFER (0.66) | KMT2AALDH1A1MEN1GFERTP53 | |
| SCHEMBL6707794 | 0.79 | GFER (0.65) | KMT2AALDH1A1MEN1PTGS2GFER | |
| SCHEMBL20006969 | 0.77 | MAPK1 (0.72) | ALDH1A1PTGS2TP53MAPK1SMN1; SMN2 | |
| SCHEMBL20006965 | 0.77 | TP53 (0.75) | KMT2AALDH1A1MEN1PTGS2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | KMT2A 503/4885ALDH1A1 98/4885MEN1 4634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.