Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 5/20 | 0.67 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.67 |
| ▸ | NT5E | P21589 | 5/20 | 0.66 |
| ▸ | CA5A | P35218 | 1/20 | 0.65 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.65 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.63 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.63 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.63 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.63 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.63 |
| ▸ | LDHA | P00338 | 1/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.63 |
| ▸ | FBP1 | P09467 | 1/20 | 0.63 |
| ▸ | SRC | P12931 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.63 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.63 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4362929 | 0.92 | CA5A (0.67) | P2RY1P2RY11NT5ECA5AIMPDH2 | |
| SCHEMBL188740 | 0.91 | CA5A (0.68) | P2RY1P2RY11NT5ECA5AIMPDH2 | |
| SCHEMBL8423402 | 0.89 | P2RY1 (0.83) | P2RY1P2RY11NT5ECA5ATAS1R3 | |
| SCHEMBL10120960 | 0.89 | P2RY1 (0.83) | P2RY1P2RY11NT5ECA5ATAS1R3 | |
| SCHEMBL8423419 | 0.89 | P2RY1 (0.83) | P2RY1P2RY11NT5ECA5ATAS1R3 | |
| SCHEMBL27183159 | 0.89 | CA5A (0.66) | P2RY1P2RY11NT5ECA5AIMPDH2 | |
| E626 SCHEMBL19222125 | 0.88 | CA5A (0.71) | P2RY1P2RY11NT5ECA5AIMPDH2 | |
| Triphosphate SCHEMBL11811171 | 0.87 | CA5A (0.64) | P2RY1P2RY11CA5AIMPDH2TAS1R3 | |
| SCHEMBL31527983 | 0.85 | IMPDH2 (0.67) | P2RY1P2RY11NT5ECA5AIMPDH2 | |
| SCHEMBL31527789 | 0.85 | CA5A (0.62) | P2RY1P2RY11NT5ECA5AIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826488-B1 | CRYSTAL OF BACTERIAL INOSINE MONOPHOSPHATE DEHYDROGENASE PRODUCED FROM PURIFIED AND ACTIVE ENZYME OBTAINED FROM PURE CULTURE OF STREPTOCOCCUS PYOGENES | THE UNIVERSITY OF CHICAGO | 2004-11-30 | — | — | US | disclosed |