SCHEMBL18876985

SCHEMBL18876985

c1ccc(-c2nc3ccccc3nc2-n2c3ccc4ccccc4c3c3c4ccccc4c(-c4ccc5sc6ccccc6c5c4)cc32)cc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HRH4 Q9H3N8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18876943 0.94 CASP1 (0.32) CASP1HSD17B10HRH4
SCHEMBL18877116 0.90 LMNA (0.33)
SCHEMBL18876978 0.87 PIM3 (0.31)
SCHEMBL18876940 0.87 CASP1 (0.37) CASP1HSD17B10HRH4
SCHEMBL18876931 0.87 CASP1 (0.39) CASP1HSD17B10HRH4
SCHEMBL18876863 0.86 ALDH1A1 (0.38)
SCHEMBL16856047 0.86 HSD17B10 (0.35) CASP1HSD17B10HRH4
SCHEMBL18876927 0.86 ALOX5 (0.35) CASP1HSD17B10HRH4
SCHEMBL22277064 0.84 CASP1 (0.34) CASP1HSD17B10HRH4
SCHEMBL19831828 0.84 HRH4 (0.36) CASP1HSD17B10HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10186669-B2 Organic electroluminescent compound and an organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2019-01-22 US disclosed
US-9997723-B2 Organic electroluminescent compound and an organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2018-06-12 US disclosed
US-9997723-B2 Organic electroluminescent compound and an organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2018-06-12 US disclosed
US-20170279056-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-09-28 US disclosed
US-20170279056-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-09-28 US disclosed
US-20170148998-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-05-25 US disclosed
US-20170148998-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10186669-B2 Organic electroluminescent compound and an organic electroluminescent device comprising the same OR10J3, OPA1, ODC1 CASP1 1763/4885HSD17B10 1899/4885HRH4 4583/4885
US-20170148998-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, OPA1, ODC1 CASP1 1763/4885HSD17B10 1899/4885HRH4 4583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.