SCHEMBL18876993

SCHEMBL18876993

COc1ccc([PH](Cc2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.57
CA4 P22748 1/20 0.48
SIGMAR1 Q99720 1/20 0.47
RAB9A P51151 2/20 0.45
NPC1 O15118 2/20 0.45
HTT P42858 1/20 0.45
ALDH1A1 P00352 3/20 0.42
MAPT P10636 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TSHR P16473 1/20 0.42
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
TRPA1 O75762 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7819280 0.92 LTA4H (0.57) LTA4HCA4SIGMAR1RAB9ANPC1
Hydrochloric Acid SCHEMBL4598689 0.91 LTA4H (0.55) LTA4HCA4SIGMAR1RAB9ANPC1
SCHEMBL24055086 0.83 SMN1; SMN2 (0.44) LTA4HRAB9ANPC1ALDH1A1MAPT
SCHEMBL7196443 0.83 ACHE (0.56) LTA4HRAB9ANPC1ALDH1A1MAPT
SCHEMBL19337297 0.82 APP (0.57) LTA4HRAB9ANPC1ALDH1A1MAPT
SCHEMBL24055085 0.81 IDO1 (0.42) LTA4HALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL5973660 0.80 MAOB (0.57) SIGMAR1ALDH1A1
SCHEMBL5083307 0.79 TSHR (0.47) LTA4HCA4SIGMAR1ALDH1A1TSHR
Hydrochloric Acid SCHEMBL4176842 0.79 MAOB (0.56) SIGMAR1ALDH1A1
Bromide SCHEMBL29076665 0.79 MAOB (0.56) SIGMAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170149080-A1 PHOSPHONIUM CATIONS AND POLYMERS INCORPORATING THEM UNIVERSITY OF DELAWARE (US) 2017-05-25 US disclosed
US-20170149080-A1 PHOSPHONIUM CATIONS AND POLYMERS INCORPORATING THEM UNIVERSITY OF DELAWARE (US) 2017-05-25 US disclosed