Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4598689 | 0.98 | LTA4H (0.55) | LTA4HCA4SIGMAR1IDO1HTT | |
| SCHEMBL18876993 | 0.92 | LTA4H (0.57) | LTA4HCA4SIGMAR1HTTNPC1 | |
| SCHEMBL19337297 | 0.85 | APP (0.57) | LTA4HNPC1RAB9A | |
| SCHEMBL837713 | 0.83 | CALM1 (0.36) | IDO1TP53TRPA1TAAR1MIF | |
| SCHEMBL24055086 | 0.83 | SMN1; SMN2 (0.44) | LTA4HIDO1NPC1RAB9ATP53 | |
| SCHEMBL7196443 | 0.83 | ACHE (0.56) | LTA4HIDO1NPC1RAB9AAGXT | |
| SCHEMBL5083307 | 0.83 | TSHR (0.47) | LTA4HCA4SIGMAR1HIF1A | |
| SCHEMBL24055085 | 0.81 | IDO1 (0.42) | LTA4HIDO1TP53AGXTTAAR1 | |
| SCHEMBL7652603 | 0.81 | LTA4H (0.53) | LTA4HSIGMAR1NPC1RAB9ATP53 | |
| Bromide SCHEMBL16180511 | 0.81 | TSHR (0.46) | LTA4HCA4SIGMAR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362160-A | Synthesis method of stilbene derivative Z-configuration isomer | 广东克冠达医药科技有限公司 | 2024-01-09 | — | — | CN | disclosed |
| US-11858889-B2 | Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230180761-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2023-06-15 | — | — | US | disclosed |
| US-20180098541-A1 | MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-12 | — | — | US | disclosed |
| US-20180007911-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2018-01-11 | — | — | US | disclosed |
| US-20180000087-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2018-01-04 | — | — | US | disclosed |
| US-20170339961-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-11-30 | — | — | US | disclosed |
| US-9795139-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-10-24 | — | — | US | disclosed |
| US-9781935-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2017-10-10 | — | — | US | disclosed |
| US-20170075219-A1 | ONIUM SALT, PHOTOACID GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, AND METHOD FOR PRODUCING DEVICE | TOYO GOSEI CO., LTD. (JP) | 2017-03-16 | — | — | US | disclosed |
| EP-1847576-A1 | Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate | FUJIFILM Corporation (JP) | 2007-10-24 | — | — | EP | disclosed |
| US-20070242120-A1 | Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate | FUJIFILM CORPORATION (JP) | 2007-10-18 | — | — | US | disclosed |
| CN-1257894-C | Phenylethenyl or phenylethynyl derivatives as glutamate receptor antagonists | HOFFMANN LA ROCHE (CH) | 2006-05-31 | — | — | CN | disclosed |
| CN-1478080-A | Phenylethenyl or phenylethinyl derivatives as glutamate receptor antagonists | - | 2004-02-25 | — | — | CN | disclosed |
| EP-0734379-B1 | 2-ARYLALKENYL-AZACYCLOALKANE DERIVATIVES AS SIGMA RECEPTOR LIGANDS, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF | PARKE DAVIS (FR) | 2001-03-07 | — | — | EP | disclosed |
| EP-0995436-A2 | Ligands for sigma receptors and their therapeutical applications | PARKE-DAVIS (FR) | 2000-04-26 | — | — | EP | disclosed |
| EP-0734379-A1 | NOVEL 2-ARYLALKENYL-AZACYCLOALKANE DERIVATIVES AS SIGMA RECEPTOR LIGANDS, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF | INSTITUT DE RECHERCHE JOUVEINAL (I.R.J) (FR) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995015948-A1 | NOVEL 2-ARYLALKENYL-AZACYCLOALKANE DERIVATIVES AS SIGMA RECEPTOR LIGANDS, PREPARATION METHOD THEREFOR AND THERAPEUTICAL USE THEREOF | INSTITUT DE RECHERCHE JOUVEINAL (FR) | 1995-06-15 | — | — | WO | disclosed |
| CN-1024796-C | Process for preparing bicyclic peroxide compounds | HOFFMANN LA ROCHE (CH) | 1994-06-01 | — | — | CN | disclosed |
| CN-1033630-A | bicyclic peroxide and preparation method thereof | HOFFMANN LA ROCHE (CH) | 1989-07-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180098541-A1 | MOLECULES HAVEING PESTICIDAL UTILIY AND INTERMEDIATES, COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | LTA4H 1199/4885CA4 1496/4885SIGMAR1 3350/4885 |
| US-20180000087-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | LTA4H 553/4885CA4 1651/4885SIGMAR1 3628/4885 |
| US-11858889-B2 | Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease | ADM2, DDAH1, BHMT | LTA4H 192/4885CA4 3551/4885SIGMAR1 3032/4885 |
| US-20230180761-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | LTA4H 553/4885CA4 1651/4885SIGMAR1 3628/4885 |
| US-20170339961-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | LTA4H 553/4885CA4 1651/4885SIGMAR1 3628/4885 |
| US-20180007911-A1 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | LTA4H 553/4885CA4 1651/4885SIGMAR1 3628/4885 |
| US-20170075219-A1 | ONIUM SALT, PHOTOACID GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, AND METHOD FOR PRODUCING DEVICE | ARCN1, ZYX, NPY1R | LTA4H 2753/4885CA4 881/4885SIGMAR1 1195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.