Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL16180511 | 0.98 | TSHR (0.46) | TSHRMAPK1MAOBHIF1AABCB1 | |
| Bromide SCHEMBL28593166 | 0.89 | TACR1 (0.48) | TSHRMAPK1MAOBHIF1AABCB1 | |
| SCHEMBL5973660 | 0.86 | MAOB (0.57) | MAOBHIF1AABCB1ALDH1A1SIGMAR1 | |
| Bromide SCHEMBL29076665 | 0.84 | MAOB (0.56) | MAOBHIF1AABCB1ALDH1A1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4176842 | 0.84 | MAOB (0.56) | MAOBHIF1AABCB1ALDH1A1SIGMAR1 | |
| SCHEMBL7819280 | 0.83 | LTA4H (0.57) | HIF1ACA4LTA4HSIGMAR1 | |
| SCHEMBL18179853 | 0.82 | CYP19A1 (0.46) | TSHRMAPK1MAOBABCB1CA4 | |
| Hydrochloric Acid SCHEMBL4598689 | 0.81 | LTA4H (0.55) | HIF1ACA4LTA4HSIGMAR1 | |
| SCHEMBL18876993 | 0.79 | LTA4H (0.57) | TSHRCA4LTA4HALDH1A1L3MBTL1 | |
| SCHEMBL28682641 | 0.79 | L3MBTL1 (0.41) | TSHRMAPK1MAOBHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004722-B2 | Method for treating hepatic encephalopathy or a disease associated with free radical mediate stress and oxidative stress with novel functionalized 1,3-benzene diols | KANNALIFE SCIENCES, INC. (US) | 2018-06-26 | — | — | US | disclosed |
| US-10004722-B2 | Method for treating hepatic encephalopathy or a disease associated with free radical mediate stress and oxidative stress with novel functionalized 1,3-benzene diols | KANNALIFE SCIENCES, INC. (US) | 2018-06-26 | — | — | US | disclosed |
| US-9939729-B2 | Resist pattern-forming method | JSR CORPORATION (JP) | 2018-04-10 | — | — | US | disclosed |
| US-9766547-B2 | Pattern forming method, actinic ray-sensitive or radiation-sensitive resin composition, resist film, method of manufacturing electronic device using the same, and electronic device | FUJIFILM CORPORATION (JP) | 2017-09-19 | — | — | US | disclosed |
| US-9766547-B2 | Pattern forming method, actinic ray-sensitive or radiation-sensitive resin composition, resist film, method of manufacturing electronic device using the same, and electronic device | FUJIFILM CORPORATION (JP) | 2017-09-19 | — | — | US | disclosed |
| US-20170157097-A1 | METHOD FOR TREATING HEPATIC ENCEPHALOPATHY OR A DISEASE ASSOCIATED WITH FREE RADICAL MEDIATE STRESS AND OXIDATIVE STRESS WITH NOVEL FUNCTIONALIZED 1,3-BENZENE DIOLS | KANNALIFE SCIENCES, INC. | 2017-06-08 | — | — | US | disclosed |
| US-20170157097-A1 | METHOD FOR TREATING HEPATIC ENCEPHALOPATHY OR A DISEASE ASSOCIATED WITH FREE RADICAL MEDIATE STRESS AND OXIDATIVE STRESS WITH NOVEL FUNCTIONALIZED 1,3-BENZENE DIOLS | KANNALIFE SCIENCES, INC. | 2017-06-08 | — | — | US | disclosed |
| US-9651863-B2 | Pattern forming method, active light sensitive or radiation sensitive resin composition, resist film, method for manufacturing electronic device, and electronic device | FUJIFILM CORPORATION (JP) | 2017-05-16 | — | — | US | disclosed |
| US-9651863-B2 | Pattern forming method, active light sensitive or radiation sensitive resin composition, resist film, method for manufacturing electronic device, and electronic device | FUJIFILM CORPORATION (JP) | 2017-05-16 | — | — | US | disclosed |
| US-9611213-B2 | Functionalized 1,3-benzene diols and their method of use for the treatment of hepatic encephalopathy | KANNALIFE SCIENCES, INC. (US) | 2017-04-04 | — | — | US | disclosed |
| EP-0934065-B1 | NOVEL CRYPTOPHYCIN DERIVATIVES AS ANTI-NEOPLASTIC AGENTS | UNIV HAWAII (US) | 2006-06-07 | — | — | EP | disclosed |
| US-6844471-B2 | Method for the conversion of a Z-isomer into E-isomer | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2005-01-18 | — | — | US | disclosed |
| WO-2004009539-A2 | METHOD FOR THE CONVERSION OF A Z-ISOMER INTO E-ISOMER | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2004-01-29 | — | — | WO | disclosed |
| US-20040015020-A1 | Method for the conversion of a Z-isomer into E-isomer | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2004-01-22 | — | — | US | disclosed |
| US-6680311-B1 | ANTICARCINOGENIC, ANTITUMOR AND ANTIPROLIFERATIVE AGENTS | ELI LILLY AND COMPANY | 2004-01-20 | — | — | US | disclosed |
| WO-2003094833-A2 | A NEW STEREOSELECTIVE ROUTE TO PRODUCE TRIS-O-SUBSTITUTED-(E)-( 3,5-DIHYDROXYPHENYL)-2-(4- HYDROXYPHENYL)ETHENE | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2003-11-20 | — | — | WO | disclosed |
| US-6552213-B1 | Oxidation and halogenation of such as 3,4',5-tribenzyloxy-dibenzylsulfide; reductive dehalogenation desulfonation; hydrolysis | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED, INDIA (IN) | 2003-04-22 | — | — | US | disclosed |
| EP-0934065-A4 | PHARMACEUTICAL COMPOUNDS | LILLY CO ELI (US) | 2000-10-11 | — | — | EP | disclosed |
| EP-0934065-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998008505-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170157097-A1 | METHOD FOR TREATING HEPATIC ENCEPHALOPATHY OR A DISEASE ASSOCIATED WITH FREE RADICAL MEDIATE STRESS AND OXIDATIVE STRESS WITH NOVEL FUNCTIONALIZED 1,3-BENZENE DIOLS | TXNRD2, KEAP1, GOT2 | TSHR 3175/4885MAPK1 1444/4885MAOB 224/4885 |
| US-20040015020-A1 | Method for the conversion of a Z-isomer into E-isomer | ECH1, CYP1A1, KEAP1 | TSHR 3806/4885MAPK1 3605/4885MAOB 1313/4885 |
| US-10004722-B2 | Method for treating hepatic encephalopathy or a disease associated with free radical mediate stress and oxidative stress with novel functionalized 1,3-benzene diols | TXNRD2, KEAP1, GOT2 | TSHR 3175/4885MAPK1 1444/4885MAOB 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.