SCHEMBL18877

SCHEMBL18877

Nn1ncc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.47
KMO O15229 1/20 0.46
CYP1A2 P05177 2/20 0.43
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
THPO P40225 1/20 0.40
CYP4Z1 Q86W10 1/20 0.40
DDB1 Q16531 1/20 0.39
CRBN Q96SW2 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
NOS2 P35228 1/20 0.39
ADRA2A P08913 2/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
TFPI2 P48307 1/20 0.37
RAB9A P51151 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL2190324 0.90 KMO (0.51) RECQLKMOCYP1A2DDB1CRBN
Carbamic Acid SCHEMBL1857014 0.88 KMO (0.54) RECQLKMOCYP1A2DDB1CRBN
SCHEMBL276288 0.73 RECQL (0.48) RECQLKMOCYP1A2ALDH1A1MAPT
SCHEMBL9123802 0.73 ELANE (0.49) RECQLKMOCYP1A2CYP11B1CYP11B2
SCHEMBL787026 0.71 RECQL (0.47) RECQLKMOCYP1A2ALDH1A1MAPT
SCHEMBL61456 0.71 RECQL (0.47) RECQLKMOCYP1A2ALDH1A1MAPT
SCHEMBL2010731 0.71 RECQL (0.47) RECQLKMOCYP1A2ALDH1A1MAPT
SCHEMBL329140 0.71 RECQL (0.47) RECQLKMOCYP1A2ALDH1A1MAPT
SCHEMBL47226 0.71 CYP1A2 (0.47) RECQLKMOCYP1A2ALDH1A1MAPT
SCHEMBL13647386 0.71 RECQL (0.47) RECQLKMOCYP1A2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1033 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080001-A Perfluoroalkyl substituted pyrimido [1,2-b ] indazole ketone compound and preparation method thereof 2026-05-26 CN claimed
US-20260076943-A1 METHOD FOR IMPROVING SKELETAL HEALTH UNIV INDIANA TRUSTEES (US) 2026-03-19 US claimed
US-20250277156-A1 USE AND METHOD INNOSPEC LIMITED (GB) 2025-09-04 US claimed
US-20250270463-A1 USE AND METHOD INNOSPEC LIMITED (GB) 2025-08-28 US claimed
CN-116063283-B 3-Amino indazole compound and application thereof 暨南大学 2025-03-25 CN claimed
EP-4514924-A1 USE AND METHOD Innospec Limited (GB) 2025-03-05 EP claimed
EP-4514925-A1 USE AND METHOD Innospec Limited (GB) 2025-03-05 EP claimed
CN-118994101-A Arylindazole ring compound, preparation method, pharmaceutical composition and application 安徽医科大学 2024-11-22 CN claimed
WO-2023209370-A1 USE AND METHOD INNOSPEC LIMITED (GB) 2023-11-02 WO claimed
WO-2023209369-A1 USE AND METHOD INNOSPEC LIMITED (GB) 2023-11-02 WO claimed
EP-0904769-B1 Keratin fibre dye compositions containing Indazole amine derivatives and dyeing method OREAL (FR) 2002-09-25 EP claimed
US-20020040508-A1 COMPOSITION FOR DYEING KERATIN FIBRES,COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE L'OREAL S.A. (FR) 2002-04-11 US claimed
WO-2001078648-A2 6-METHYLNICOTINAMIDE DERIVATIVES AS ANTIVIRAL AGENTS DONG WHA PHARM. IND. CO., LTD. (KR) 2001-10-25 WO claimed
EP-0981320-A1 COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE L'OREAL (FR) 2000-03-01 EP claimed
WO-1998051268-A1 COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE L'OREAL (FR) 1998-11-19 WO claimed
EP-0848613-A1 ANALOGS FOR SPECIFIC OLIGOSACCHARIDE-NEUREGULIN INTERACTIONS AND USES THEREOF CAMBRIDGE NEUROSCIENCE, INC. (US) 1998-06-24 EP claimed
WO-1997009051-A1 ANALOGS FOR SPECIFIC OLIGOSACCHARIDE-NEUREGULIN INTERACTIONS AND USES THEREOF CAMBRIDGE NEUROSCIENCE, INC. (US) 1997-03-13 WO claimed
WO-1992000981-A1 NOVEL 3-SUBSTITUTED CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF DAE WOONG PHARMACEUTICAL CO., LTD. (KR) 1992-01-23 WO claimed
US-5017471-A Reagent for peroxidase detection EPITOPE, INC. (US) 1991-05-21 US claimed
US-4999267-A ELECTROGRAPHY MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1991-03-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020040508-A1 COMPOSITION FOR DYEING KERATIN FIBRES,COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE KRT18, KLK5, H1-5 RECQL 1620/4885KMO 47/4885CYP1A2 174/4885
US-20260076943-A1 METHOD FOR IMPROVING SKELETAL HEALTH MYOF, CKMT1A; CKMT1B, MUSK RECQL 4329/4885KMO 71/4885CYP1A2 2928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.