SCHEMBL47226

SCHEMBL47226

Cn1ncc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
RECQL P46063 1/20 0.47
TRPA1 O75762 1/20 0.46
KMO O15229 1/20 0.46
CDK8 P49336 1/20 0.43
ALDH1A1 P00352 3/20 0.40
MAPT P10636 3/20 0.40
HPGD P15428 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
SLC9A1 P19634 1/20 0.40
KEAP1 Q14145 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
GAA P10253 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29487677 1.00 CYP1A2 (0.47) CYP1A2RECQLTRPA1KMOCDK8
Fluoride SCHEMBL31655450 0.98 CYP1A2 (0.46) CYP1A2RECQLTRPA1KMOCDK8
SCHEMBL463262 0.88 KMO (0.46) CYP1A2RECQLTRPA1KMOCDK8
SCHEMBL29487791 0.87 TRPA1 (0.42) CYP1A2RECQLTRPA1KMOCDK8
Formic Acid SCHEMBL27515529 0.87 KMO (0.45) CYP1A2RECQLTRPA1KMOCDK8
SCHEMBL28449338 0.85 RECQL (0.41) CYP1A2RECQLTRPA1KMOCDK8
SCHEMBL31097138 0.85 RECQL (0.43) CYP1A2RECQLTRPA1KMOCDK8
Quinoline SCHEMBL27698764 0.84 ALDH1A1 (0.57) CYP1A2RECQLTRPA1KMOALDH1A1
SCHEMBL29487819 0.83 TRPA1 (0.39) CYP1A2RECQLTRPA1KMOCDK8
Trifluoroacetic Acid SCHEMBL31197687 0.82 KMO (0.49) RECQLTRPA1KMOALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1841 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136781-A ROR 1-targeted inhibitor and synthesis method and application thereof 北京大学 2025-06-13 CN claimed
WO-2024193328-A1 INDAZOLE SUBSTITUTED PODOPHYLLOTOXIN DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 汤亚杰 2024-09-26 WO claimed
EP-3356387-B1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS UNIV MONASH (AU) 2024-06-26 EP claimed
CN-117430562-A 4-methyl-2-oxo-3, 6-dihydropyrimidine compound and preparation method and application thereof 中山大学 2024-01-23 CN claimed
CN-112573978-B High-efficiency halogenation synthesis method of aryl halide 北京大学 2022-05-13 CN claimed
CN-108350034-B Antimicrobial polymyxin derived compounds 莫纳什大学 2022-03-11 CN claimed
EP-3924349-A2 AMINO ACID DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES The Roskamp Institute (US) 2021-12-22 EP claimed
CN-113614074-A Amino acid derivatives for the treatment of inflammatory diseases 罗斯坎普研究所 2021-11-05 CN claimed
EP-3894396-A1 2-OXOQUINAZOLINE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS Ideaya Biosciences, Inc. (US) 2021-10-20 EP claimed
CN-113166078-A 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors 伊迪亚生物科学有限公司 2021-07-23 CN claimed
US-5559110-A HIV ANTIVIRAL, GOOD SYSTEMIC ABSORPTION ADMINISTERED BY MOUTH THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1996-09-24 US claimed
US-5543517-A VIRICIDES THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1996-08-06 US claimed
US-5532357-A Method for preparing N-monosubstituted and N,N'-disubstituted unsymmetrical cyclic ureas THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1996-07-02 US claimed
WO-1996000708-A1 METHOD FOR PREPARING ALKYLATING AGENTS AND THEIR USE FOR ALKYLATING CYCLIC UREAS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-11 WO claimed
WO-1994019329-A1 SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-09-01 WO claimed
EP-0291787-B1 Novel substituted silyl alkylene amines MERRELL DOW PHARMA (US) 1994-03-16 EP claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
EP-0351385-A2 New amidino and guanidino derivatives BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) 1990-01-17 EP claimed
EP-0291787-A1 Novel substituted silyl alkylene amines MERRELL DOW PHARMACEUTICALS INC. (US) 1988-11-23 EP claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed