Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21702634 | 0.84 | TRPA1 (0.46) | TRPA1MAPK1 | |
| SCHEMBL12744730 | 0.83 | TRPA1 (0.36) | TRPA1MAPK1 | |
| SCHEMBL18940855 | 0.83 | — | — | |
| SCHEMBL23587270 | 0.83 | — | — | |
| SCHEMBL23055006 | 0.78 | HDAC3 (0.32) | — | |
| SCHEMBL22419898 | 0.75 | — | — | |
| SCHEMBL20808343 | 0.71 | — | — | |
| SCHEMBL20879395 | 0.71 | — | — | |
| SCHEMBL18569616 | 0.71 | — | — | |
| SCHEMBL12510761 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11141495-B2 | MRI imaging of amyloid plaque using liposomes | TEXAS CHILDREN'S HOSPITAL (US) | 2021-10-12 | — | — | US | disclosed |
| US-20200179540-A1 | MRI IMAGING OF AMYLOID PLAQUE USING LIPOSOMES | TEXAS CHILDREN'S HOSPITAL | 2020-06-11 | — | — | US | disclosed |
| US-20200069820-A1 | MRI IMAGING OF AMYLOID PLAQUE USING LIPOSOMES | TEXAS CHILDREN'S HOSPITAL | 2020-03-05 | — | — | US | disclosed |
| US-10463660-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxymorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2019-11-05 | — | — | US | disclosed |
| US-10258696-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2019-04-16 | — | — | US | disclosed |
| US-20170143839-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof | ALTER DOMUS (US) LLC | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11141495-B2 | MRI imaging of amyloid plaque using liposomes | APP, PSEN2, APBA1 | TRPA1 2020/4885MAPK1 3241/4885 |
| US-20200179540-A1 | MRI IMAGING OF AMYLOID PLAQUE USING LIPOSOMES | APP, PSEN2, APBA1 | TRPA1 2020/4885MAPK1 3241/4885 |
| US-10463660-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxymorphone, prodrugs, methods of making and use thereof | OPRM1, OPRK1, OPRD1 | TRPA1 2443/4885MAPK1 3221/4885 |
| US-20200069820-A1 | MRI IMAGING OF AMYLOID PLAQUE USING LIPOSOMES | APP, PSEN2, APBA1 | TRPA1 2020/4885MAPK1 3241/4885 |
| US-20170143839-A1 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydromorphone, Prodrugs, Methods of Making and Use Thereof | OPRM1, OPRK1, CYP2D6 | TRPA1 3578/4885MAPK1 2573/4885 |
| US-10258696-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydromorphone, prodrugs, methods of making and use thereof | OPRM1, OPRK1, CYP2D6 | TRPA1 3578/4885MAPK1 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.