SCHEMBL18878618

SCHEMBL18878618

CC[C@H](C(C)=O)N1CCCC1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
LMNA P02545 3/20 0.33
DPP4 P27487 3/20 0.33
FAP Q12884 3/20 0.33
DPP8 Q6V1X1 3/20 0.33
DPP9 Q86TI2 3/20 0.33
DPP7 Q9UHL4 3/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23959724 0.82 DPP4 (0.33) LMNADPP4FAPDPP8DPP9
SCHEMBL27800027 0.81 KDM4E (0.50) KDM4ELMNASIGMAR1MEN1POLB
SCHEMBL27800028 0.81 KDM4E (0.50) KDM4ELMNASIGMAR1MEN1POLB
SCHEMBL2026586 0.79 KDM4E (0.46) KDM4ELMNADPP4FAPDPP8
SCHEMBL10604442 0.79 SIGMAR1 (0.32) LMNADPP4FAPDPP8DPP9
SCHEMBL18519293 0.78 RECQL (0.36) KDM4ELMNACA12CA1CA2
SCHEMBL19883371 0.73 KDM4E (0.35) KDM4ELMNADPP4FAPDPP8
SCHEMBL26592987 0.72 HRH3 (0.34) KDM4EHRH3
SCHEMBL13080712 0.71 L3MBTL1 (0.38) KDM4EHRH3L3MBTL1
SCHEMBL24738799 0.71 L3MBTL1 (0.38) KDM4EHRH3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170146549-A1 ISOBARIC MASS LABELS ELECTROPHORETICS LIMITED (GB) 2017-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170146549-A1 ISOBARIC MASS LABELS SRMS, PTMS, QPCTL KDM4E 849/4885LMNA 49/4885DPP4 2231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.