SCHEMBL1893689

SCHEMBL1893689

CCc1cc(CC)c(-c2c(-c3cc(CC)c(CC)cc3CC)c(-c3cc(CC)c(CC)cc3CC)c3c(c2-c2cc(CC)c(CC)cc2CC)=c2ccccc2=3)cc1CC

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
P2RY2 P41231 1/20 0.31
P2RY4 P51582 1/20 0.31
GABRA1 P14867 2/20 0.30
GABRB2 P47870 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1887868 0.85 TLR8 (0.34) HSP90AA1
SCHEMBL9723265 0.80 ALDH1A1 (0.47) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL27792377 0.78 NPC1 (0.33) HSP90AA1NPC1ALDH1A1LMNAMAPT
SCHEMBL1886830 0.76 MEN1 (0.31)
SCHEMBL5048794 0.74 TSHR (0.38) HSP90AA1
SCHEMBL1888188 0.73 MEN1 (0.31)
SCHEMBL1887840 0.71 NPC1 (0.35) NPC1ALDH1A1LMNAMAPK1RAB9A
SCHEMBL1885181 0.71 NPC1 (0.35) NPC1ALDH1A1LMNAMAPK1RAB9A
SCHEMBL10783900 0.69 GABRA1 (0.46) LMNAMAPTL3MBTL1GABRA1GABRB2
SCHEMBL7006718 0.69 GABRA1 (0.46) LMNAMAPTL3MBTL1GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-20100104879-A1 CLEAR HARD COAT FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND DISPLAY DEVICE EMPLOYING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed