SCHEMBL18879673

SCHEMBL18879673

Cc1ccc2scnc2c1C#N

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.32
CYP2C19 P33261 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
XDH P47989 1/20 0.32
SLC22A12 Q96S37 1/20 0.32
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31
ALDH1A1 P00352 3/20 0.31
POLB P06746 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 2/20 0.31
GAA P10253 1/20 0.31
KDM4E B2RXH2 2/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15264324 0.79 ADORA1 (0.33) CYP1A2CYP2C19XDHSLC22A12ALDH1A1
SCHEMBL15263596 0.79 XDH (0.32) XDHSLC22A12ALDH1A1HSD17B10
SCHEMBL7458773 0.75 ALDH1A1 (0.35) ALDH1A1MAPK1SMN1; SMN2NPSR1HSD17B10
SCHEMBL15278587 0.73
SCHEMBL25079249 0.72 P4HB (0.39) HTTALDH1A1MAPK1SMN1; SMN2NPSR1
SCHEMBL31389476 0.72 ALDH1A1 (0.33) ALDH1A1MAPK1SMN1; SMN2NPSR1HSD17B10
SCHEMBL28015184 0.72 ALDH1A1 (0.33) ALDH1A1MAPK1SMN1; SMN2NPSR1HSD17B10
SCHEMBL18876087 0.72 ALDH1A1 (0.33) ALDH1A1MAPK1SMN1; SMN2NPSR1HSD17B10
SCHEMBL22025575 0.72 ALDH1A1 (0.33) ALDH1A1MAPK1SMN1; SMN2NPSR1HSD17B10
SCHEMBL6129362 0.72 ALDH1A1 (0.33) ALDH1A1MAPK1SMN1; SMN2NPSR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11193065-B2 Liquid crystal composition, method of producing the same, and retardation film constituted from the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-12-07 US disclosed
US-20190276744-A1 LIQUID CRYSTAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-09-12 US disclosed
US-20170306234-A1 LIQUID CRYSTAL COMPOSITION, METHOD OF PRODUCING THE SAME, AND RETARDATION FILM CONSTITUTED FROM THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-26 US disclosed
US-20170145312-A1 LIQUID CRYSTAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-25 US disclosed