SCHEMBL18883181

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18883182	0.86	ALDH1A1 (0.63)	ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
	SCHEMBL9679472	0.82	ALDH1A1 (0.60)	ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
	SCHEMBL10889886	0.77	ALDH1A1 (0.81)	ALDH1A1SMN1; SMN2MAPK1TSHRFKBP1A
	SCHEMBL10884364	0.77	ALDH1A1 (0.81)	ALDH1A1SMN1; SMN2MAPK1TSHRFKBP1A
	SCHEMBL1554157	0.75	ALDH1A1 (0.72)	ALDH1A1SMN1; SMN2MAPK1TSHRFKBP1A
	SCHEMBL10888087	0.74	ALDH1A1 (0.55)	ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
	SCHEMBL21024705	0.72	ALDH1A1 (0.45)	ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
	SCHEMBL9679529	0.72	SMN1; SMN2 (0.72)	ALDH1A1SMN1; SMN2MAPK1TSHRFKBP1A
	SCHEMBL1554443	0.72	ALDH1A1 (0.72)	ALDH1A1SMN1; SMN2MAPK1TSHRFKBP1A
	SCHEMBL18883201	0.72	ALDH1A1 (0.72)	ALDH1A1SMN1; SMN2MAPK1TSHRHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.