SCHEMBL18889482

SCHEMBL18889482

O=C1C=C(Br)C(=O)C(Br)=C1Br

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.41
P4HB P07237 1/20 0.38
ALOX5 P09917 1/20 0.34
PTGS2 P35354 1/20 0.34
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14010274 0.76 AURKA (0.41) PTPRCP4HBALOX5PTGS2MAPT
SCHEMBL14129376 0.73 PTPRC (0.48) PTPRCP4HBALOX5PTGS2MEN1
SCHEMBL12481392 0.70 PTPRC (0.43) PTPRCP4HBALOX5PTGS2
SCHEMBL299196 0.70 PTPRC (0.43) PTPRCP4HBALOX5PTGS2
SCHEMBL18992911 0.69 MAPT (0.41) PTPRCP4HBALOX5PTGS2MEN1
SCHEMBL10801809 0.67 PTPRC (0.31) PTPRC
SCHEMBL891446 0.65 ALOX5 (0.56) PTPRCP4HBALOX5PTGS2MEN1
SCHEMBL11238835 0.63
SCHEMBL300031 0.63 MAOA (0.37) MEN1MAPTMAPK1KMT2A
SCHEMBL1392535 0.61 P2RX7 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10174204-B2 Method for preparation of carbon quantum dots and application INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) 2019-01-08 US claimed
US-20170152385-A1 METHOD FOR PREPARATION OF CARBON QUANTUM DOTS AND APPLICATION INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES 2017-06-01 US claimed
US-20170152141-A1 METHOD FOR PREPARING HETEROGENEOUS METAL-FREE FENTON CATALYST AND APPLICATION INSTITUTE OF PROCESS ENGINEERING CHINESE ACADEMY OF SCIENCES 2017-06-01 US claimed
US-10174204-B2 Method for preparation of carbon quantum dots and application INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) 2019-01-08 US disclosed
US-20170152385-A1 METHOD FOR PREPARATION OF CARBON QUANTUM DOTS AND APPLICATION INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES 2017-06-01 US disclosed
US-20170152141-A1 METHOD FOR PREPARING HETEROGENEOUS METAL-FREE FENTON CATALYST AND APPLICATION INSTITUTE OF PROCESS ENGINEERING CHINESE ACADEMY OF SCIENCES 2017-06-01 US disclosed