SCHEMBL891446

SCHEMBL891446

O=C1C=C(Br)C(=O)C(Br)=C1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.56
PTGS2 P35354 1/20 0.56
BACE1 P56817 1/20 0.38
TTR P02766 1/20 0.37
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
MAPK1 P28482 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
USP2 O75604 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HKDC1 Q2TB90 1/20 0.35
PTPRC P08575 1/20 0.35
P4HB P07237 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28225131 0.97 ALOX5 (0.54) ALOX5PTGS2BACE1TTRMEN1
SCHEMBL11300666 0.82 ALOX5 (0.43) ALOX5PTGS2
SCHEMBL31415084 0.80 ALOX5 (0.46) ALOX5PTGS2BACE1
SCHEMBL7115894 0.74 ALOX5 (1.00) ALOX5PTGS2BACE1MEN1MAPT
SCHEMBL15071870 0.74 ALOX5 (0.42) ALOX5PTGS2
SCHEMBL1683186 0.67 TTR (0.44) ALOX5PTGS2TTRMEN1MAPT
SCHEMBL14129376 0.67 PTPRC (0.48) ALOX5PTGS2TTRMEN1MAPT
SCHEMBL783397 0.67
SCHEMBL18889482 0.65 PTPRC (0.41) ALOX5PTGS2MEN1MAPTMAPK1
SCHEMBL18992911 0.63 MAPT (0.41) ALOX5PTGS2MEN1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12557811-B2 Effective and eco-friendly disinfectant THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2026-02-24 US claimed
CN-119977819-A Organic electric energy transfer eutectic crystal with near infrared light thermal characteristics and preparation method of light heat storage fiber thereof 苏州大学 2025-05-13 CN claimed
CN-119638986-A Organic positive electrode material of ion battery and preparation method thereof 燕山大学 2025-03-18 CN claimed
US-20240196888-A1 EFFECTIVE AND ECO-FRIENDLY DISINFECTANT THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-06-20 US claimed
CN-118104652-A Effective and environment-friendly disinfectant 香港科技大学 2024-05-31 CN claimed
CN-114113370-B Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2024-03-26 CN claimed
CN-116678983-A Method for simultaneously determining halogenated benzoquinone substances in water by membrane solid phase extraction-liquid chromatography-mass spectrometry 衢州市疾病预防控制中心 2023-09-01 CN claimed
CN-114113370-A Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2022-03-01 CN claimed
CN-111721756-A Alkaline phosphatase activity detection kit and detection method 中国农业科学院北京畜牧兽医研究所 2020-09-29 CN claimed
CN-108593802-A Gas chromatography-electron capture detector detection method of halogenated benzoquinone 天津大学 2018-09-28 CN claimed
CN-102809559-B Method for detecting halogenated aromatic organic matter RES CT ECO ENVIRONMENTAL SCIEN 2015-06-17 CN claimed
CN-102809559-A Method for detecting halogenated aromatic organic matter RES CT ECO ENVIRONMENTAL SCIEN 2012-12-05 CN claimed
EP-0120296-B1 POLY(ARYL ETHER-ARYLSULFONE) TRANSPARENT MOULDING COMPOUNDS WITH LOW INFLAMMABILITY, PROCESS FOR THEIR MANUFACTURE, AND THEIR USE BASF Aktiengesellschaft (DE) 1986-06-04 EP claimed
US-4551493-A POLY(2,6-DIBROMOPHENYLENE-1,4-OXIDE) FLAMEPROOFING AGENT BASF AKTIENGESELLSCHAFT (DE) 1985-11-05 US claimed
JP-58113859-A None JP disclosed
US-12557811-B2 Effective and eco-friendly disinfectant THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2026-02-24 US disclosed
US-12391781-B2 Black particles, black coating material, coating film, and black matrix for color filters SEKISUI CHEMICAL CO., LTD. (JP) 2025-08-19 US disclosed
US-4551493-A POLY(2,6-DIBROMOPHENYLENE-1,4-OXIDE) FLAMEPROOFING AGENT BASF AKTIENGESELLSCHAFT (DE) 1985-11-05 US disclosed
JP-S58113859-A METHOD AND APPARATUS FOR ANALYZING VITAMIN B6 SHIMADZU CORP 1983-07-06 JP disclosed
US-3954906-A ELECTROSTATOGRAPHIC IMAGING XEROX CORPORATION (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12557811-B2 Effective and eco-friendly disinfectant DDT, DRD1, DRD4 ALOX5 2262/4885PTGS2 3800/4885BACE1 2470/4885
US-20240196888-A1 EFFECTIVE AND ECO-FRIENDLY DISINFECTANT DDT, DERL1, DUS2 ALOX5 702/4885PTGS2 3292/4885BACE1 2324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.