Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | TP53 | P04637 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18890609 | 0.89 | NPC1 (0.58) | AMY1AALDH1A1TP53MEN1KMT2A | |
| SCHEMBL18890544 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TP53MEN1KMT2AKDM4E | |
| SCHEMBL1170729 | 0.82 | ALDH1A1 (0.57) | AMY1AALDH1A1TP53MEN1KMT2A | |
| SCHEMBL18906377 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TP53MEN1KMT2AKDM4E | |
| SCHEMBL18906374 | 0.80 | ALDH1A1 (0.47) | AMY1AALDH1A1TP53MEN1KMT2A | |
| SCHEMBL3340524 | 0.78 | ALDH1A1 (0.58) | AMY1AALDH1A1TP53MEN1KMT2A | |
| SCHEMBL7038591 | 0.77 | CHEK2 (0.56) | ALDH1A1TP53MEN1KMT2AKDM4E | |
| SCHEMBL18906373 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TP53MEN1KMT2AKDM4E | |
| SCHEMBL7033087 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1TP53KDM4EPOLBNPC1 | |
| SCHEMBL18890639 | 0.76 | MMP2 (0.58) | ALDH1A1TP53MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152245-A1 | BENZIMIDAZOLE COMPOUNDS AND THEIR APPLICATION IN CARDIOVASCULAR DISEASES | NATIONAL TAIWAN UNIVERSITY (TW) | 2017-06-01 | — | — | US | disclosed |
| US-20170152245-A1 | BENZIMIDAZOLE COMPOUNDS AND THEIR APPLICATION IN CARDIOVASCULAR DISEASES | NATIONAL TAIWAN UNIVERSITY (TW) | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152245-A1 | BENZIMIDAZOLE COMPOUNDS AND THEIR APPLICATION IN CARDIOVASCULAR DISEASES | TNNI3, PDGFRA, PDGFRB | AMY1A 3791/4885DNMT1 3607/4885ALDH1A1 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.