Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18891153 | 1.00 | KMT2A (0.53) | KMT2AMEN1PKMMAPTPOLB | |
| SCHEMBL18891154 | 0.88 | MAPT (0.50) | KMT2AMEN1PKMMAPTPOLB | |
| SCHEMBL18891034 | 0.88 | MAPT (0.50) | KMT2AMEN1PKMMAPTPOLB | |
| SCHEMBL18883891 | 0.86 | HCAR3 (0.44) | KMT2AMEN1PKMMAPTPOLB | |
| SCHEMBL18883867 | 0.86 | HCAR3 (0.44) | KMT2AMEN1PKMMAPTPOLB | |
| SCHEMBL18883866 | 0.84 | ALDH1A1 (0.48) | PKMMAPTPOLBGAALMNA | |
| SCHEMBL18883850 | 0.84 | KAT2B (0.51) | KMT2APKMMAPTPOLBLMNA | |
| SCHEMBL18883881 | 0.84 | ALDH1A1 (0.48) | PKMMAPTPOLBGAALMNA | |
| SCHEMBL18883872 | 0.84 | KAT2B (0.51) | KMT2APKMMAPTPOLBLMNA | |
| SCHEMBL18891033 | 0.82 | PDE3B (0.36) | KMT2AMEN1PKMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145156-A1 | Catalysis and Catalysts for Polymerization | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145156-A1 | Catalysis and Catalysts for Polymerization | TST, CBR3, MSRB3 | KMT2A 1906/4885MEN1 2802/4885PKM 2581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.