Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | HTR2B | P41595 | 3/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12153136 | 0.85 | HTR2A (0.60) | HTR2AHTR2BSIGMAR1ADRA2CSLC6A4 | |
| SCHEMBL13200644 | 0.83 | SIGMAR1 (0.52) | SIGMAR1CYP3A4CYP2D6TP53TSHR | |
| SCHEMBL4238528 | 0.83 | HTR2A (0.66) | HTR2AHTR2BSIGMAR1ADRA2CSLC6A4 | |
| SCHEMBL9248064 | 0.82 | SIGMAR1 (0.74) | HTR2AHTR2BSIGMAR1ADRA2CSLC6A4 | |
| SCHEMBL9472690 | 0.82 | SIGMAR1 (0.74) | HTR2AHTR2BSIGMAR1ADRA2CSLC6A4 | |
| SCHEMBL9156429 | 0.82 | SIGMAR1 (0.74) | HTR2AHTR2BSIGMAR1ADRA2CSLC6A4 | |
| SCHEMBL13200640 | 0.82 | CYP2D6 (0.47) | HTR2AHTR2BSIGMAR1ADRA2CSLC6A4 | |
| SCHEMBL18893310 | 0.80 | ALDH1A1 (0.73) | HTR2AHTR2BSIGMAR1ADRA2CSLC6A4 | |
| SCHEMBL22957705 | 0.79 | MEN1 (0.43) | HTR2AHTR2BSIGMAR1ADRA2CSLC6A4 | |
| SCHEMBL27841361 | 0.79 | MAPT (0.50) | HTR2AHTR2BSIGMAR1ADRA2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | THE UNITED STATES OF AMERICA AS REPRESENTED BY SECRETARY DEPT OF HEALTH AND HUMAN SERVICE (US) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | RXFP1, RXFP2, RXFP3 | HTR2A 339/4885HTR2B 403/4885SIGMAR1 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.