Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22957707 | 0.87 | MEN1 (0.45) | MEN1KMT2ACASRHDAC4MEF2D | |
| SCHEMBL13074511 | 0.80 | BCHE (0.49) | MEN1KMT2AHDAC4MEF2DKDM4E | |
| SCHEMBL8292121 | 0.80 | MRGPRX4 (0.48) | HDAC4MEF2DALDH1A1MAPTKDM4E | |
| SCHEMBL12933252 | 0.79 | HDAC4 (0.45) | MEN1KMT2AHDAC4MEF2DALDH1A1 | |
| SCHEMBL18893217 | 0.79 | HTR2A (0.64) | ALDH1A1CYP2D6SIGMAR1LMNAMAPT | |
| SCHEMBL22957720 | 0.78 | BCHE (0.49) | MEN1KMT2AHDAC4MEF2DHTR2A | |
| SCHEMBL5947773 | 0.78 | CASR (0.57) | MEN1KMT2ACASRCYP2C19CYP17A1 | |
| SCHEMBL8186760 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTDRD3CYP2C19CYP17A1 | |
| SCHEMBL13200644 | 0.77 | SIGMAR1 (0.52) | MEN1KMT2AALDH1A1CYP2D6SIGMAR1 | |
| SCHEMBL8179186 | 0.77 | TAAR1 (0.46) | MEN1KMT2AALDH1A1SIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | RIPK1, RIPK3, RIPK4 | MEN1 3915/4885KMT2A 1255/4885CASR 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.