Cysteine

Cysteine

SCHEMBL1889352

NCCC1=CC(=O)NC1=O.N[C@@H](CS)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.46
SLC7A11 Q9UPY5 1/20 0.46
GSR P00390 1/20 0.31
GRIA1 P42261 2/20 0.31
GRIA2 P42262 2/20 0.31
GRIA3 P42263 2/20 0.31
GRIA4 P48058 2/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31
GRIK5 Q16478 1/20 0.31
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30
GRIK1 P39086 1/20 0.30
GRIK2 Q13002 1/20 0.30
GRIK3 Q13003 1/20 0.30
ITGB3 P05106 1/20 0.30
ITGA2B P08514 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28734533 0.81
Cysteine SCHEMBL19359143 0.79 PTGS1 (0.52) PTGS1SLC7A11GRIA1GRIA3IDO1
Cysteine SCHEMBL19359142 0.79 PTGS1 (0.52) PTGS1SLC7A11GRIA1GRIA3IDO1
Bromide SCHEMBL18044121 0.78
Hydrochloric Acid SCHEMBL15994560 0.78
SCHEMBL9315085 0.77 SLC7A5 (0.43) PTGS1GRIA1GRIA2GRIA3GRIA4
SCHEMBL9315113 0.77 SLC7A5 (0.43) PTGS1GRIA1GRIA2GRIA3GRIA4
Trifluoroacetic Acid SCHEMBL13722329 0.76 HRH4 (0.39)
Cysteine SCHEMBL15417993 0.74 PTGS1 (0.84) PTGS1SLC7A11GSRGRIA1GRIA2
Cysteine SCHEMBL15418989 0.74 PTGS1 (0.84) PTGS1SLC7A11GSRGRIA1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785637-B2 Carboxamide-substituted dyes for analytical applications ATTO-TEC GMBH (DE) 2014-07-22 US disclosed
US-20130323851-A1 CARBOXAMIDE-SUBSTITUTED DYES FOR ANALYTICAL APPLICATIONS ATTO-TEC GMBH (DE) 2013-12-05 US disclosed
US-8530660-B2 Carboxamide-substituted dyes for analytical applications ATTO-TEC GMBH (DE) 2013-09-10 US disclosed
US-20110223677-A1 CARBOXAMIDE-SUBSTITUTED DYES FOR ANALYTICAL APPLICATIONS ATTO-TEC GMBH (DE) 2011-09-15 US disclosed
US-7935822-B2 Carboxamide-substituted dyes for analytical applications ATTO-TEC GMBH (DE) 2011-05-03 US disclosed
US-20060154251-A1 Carboxamide-substituted dyes for analytical applications ATTO-TEC GMBH (DE) 2006-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060154251-A1 Carboxamide-substituted dyes for analytical applications CPS1, CYCS, PFAS PTGS1 3986/4885SLC7A11 1914/4885GSR 655/4885
US-20110223677-A1 CARBOXAMIDE-SUBSTITUTED DYES FOR ANALYTICAL APPLICATIONS CPS1, CYCS, PFAS PTGS1 3986/4885SLC7A11 1914/4885GSR 655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.