Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035979 | 0.92 | MEN1 (0.65) | MEN1KMT2ARECQLEPHX1ALDH1A1 | |
| SCHEMBL840400 | 0.87 | MEN1 (0.56) | MEN1KMT2ARECQLEPHX1ALDH1A1 | |
| SCHEMBL7750774 | 0.81 | MEN1 (0.67) | MEN1KMT2ARECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL17229157 | 0.79 | MEN1 (1.00) | MEN1KMT2ARECQLEPHX1ALDH1A1 | |
| SCHEMBL10101148 | 0.79 | MEN1 (0.89) | MEN1KMT2ARECQLEPHX1ALDH1A1 | |
| SCHEMBL3950393 | 0.79 | ALDH1A1 (0.40) | MEN1KMT2AEPHX1ALDH1A1POLB | |
| SCHEMBL26066649 | 0.79 | ALDH1A1 (0.40) | MEN1KMT2AEPHX1ALDH1A1POLB | |
| SCHEMBL10061687 | 0.78 | KDM4E (0.58) | MEN1KMT2AEPHX1ALDH1A1POLB | |
| SCHEMBL5405580 | 0.78 | ALDH1A1 (0.39) | MEN1KMT2AEPHX1ALDH1A1POLB | |
| SCHEMBL21078226 | 0.78 | CASP2 (0.57) | MEN1KMT2AEPHX1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663466-B2 | Aryl dihydropyridinones and piperidinone MGAT2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-05-30 | — | — | US | disclosed |