Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793877 | 0.90 | HTR1B (0.42) | KDM4ETAAR1LTA4HPLA2G2AHTR1B | |
| SCHEMBL5256020 | 0.88 | HTR1B (0.37) | KDM4ETAAR1HTR1B | |
| SCHEMBL6238419 | 0.87 | JAK2 (0.33) | KDM4ETAAR1MAPK1SMN1; SMN2HPGD | |
| SCHEMBL2008537 | 0.83 | KCNH2 (0.32) | KDM4ETAAR1ALDH1A1 | |
| SCHEMBL5253475 | 0.83 | — | — | |
| SCHEMBL8217123 | 0.82 | KMT2A (0.33) | KDM4EMEN1KMT2A | |
| SCHEMBL126227 | 0.79 | ALDH1A1 (0.34) | KDM4ELTA4HMAPK1TP53RAB9A | |
| SCHEMBL2458787 | 0.79 | — | — | |
| SCHEMBL8583545 | 0.79 | — | — | |
| SCHEMBL348920 | 0.79 | ALDH1A1 (0.48) | SMN1; SMN2CYP3A4MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664637-A | Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2014-03-26 | — | — | CN | claimed |
| CN-101784188-A | Alkynyl phenyl derivative compounds for the treatment of ophthalmic diseases and disorders | ACUCELA INC | 2010-07-21 | — | — | CN | claimed |
| EP-0958294-A1 | 2-(1,2,4-TRIAZOLE-1-YL)-1,3,4-THIADIAZOLE DERIVATIVES HAVING AN EFFECT ON THE C.N.S. AND THE HEART | EGIS GYOGYSZERGYAR (HU) | 1999-11-24 | — | — | EP | claimed |
| WO-1998030561-A1 | 2-(1,2,4-TRIAZOLE-1-YL)-1,3,4-THIADIAZOLE DERIVATIVES HAVING AN EFFECT ON THE C.N.S. AND THE HEART | EGIS Gyógyszergyár Rt. (HU) | 1998-07-16 | — | — | WO | claimed |
| EP-0282127-B1 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | PROCTER & GAMBLE (US) | 1994-02-02 | — | — | EP | claimed |
| US-5099030-A | Phenols or phenolic ethers | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-24 | — | — | US | claimed |
| EP-0282127-A2 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | THE PROCTER & GAMBLE COMPANY (US) | 1988-09-14 | — | — | EP | claimed |
| EP-0058890-B1 | ANTITHROMBOTIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-09-26 | — | — | EP | claimed |
| EP-0058890-A1 | Antithrombotic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-01 | — | — | EP | claimed |
| CN-115960032-A | Aryloxy propanol amine beta-adrenaline receptor ligand with beta-arrestin biased agonistic activity and application thereof | 复旦大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-105541769-A | Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2016-05-04 | — | — | CN | disclosed |
| CN-103664637-B | Be used for the treatment of ophthalmic diseases and disorderly alkynyl phenyl derivative compounds | ACUCELA INC. (US) | 2016-02-03 | — | — | CN | disclosed |
| CN-105189506-A | Compounds and compositions for the treatment of parasitic diseases | NOVARTIS AG | 2015-12-23 | — | — | CN | disclosed |
| CN-105101970-A | Beta-lactamase inhibitors | VENATORX PHARMACEUTICALS INC | 2015-11-25 | — | — | CN | disclosed |
| EP-0260066-B1 | TAMOXIFEN DERIVATIVES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-05-09 | — | — | EP | disclosed |
| US-4839155-A | Iodotamoxifen derivatives and use for estrogen receptor-positive breast cancer detection and therapy | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1989-06-13 | — | — | US | disclosed |
| EP-0282127-A2 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | THE PROCTER & GAMBLE COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0260066-A1 | Tamoxifen derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-03-16 | — | — | EP | disclosed |
| EP-0058890-B1 | ANTITHROMBOTIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-09-26 | — | — | EP | disclosed |
| EP-0058890-A1 | Antithrombotic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-01 | — | — | EP | disclosed |