SCHEMBL126227

SCHEMBL126227

CCCOc1[c]cccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
LTA4H P09960 3/20 0.34
TLR8 Q9NR97 1/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
LMNA P02545 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPT P10636 2/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49991 0.90 LTA4H (0.46) ALDH1A1LTA4HTLR8CYP1A2CYP2C9
SCHEMBL7281298 0.89 L3MBTL1 (0.37) ALDH1A1LTA4HKMT2ALMNAMAPT
SCHEMBL167283 0.88 LTA4H (0.46) ALDH1A1LTA4HTLR8KMT2AMEN1
SCHEMBL27670047 0.88 LTA4H (0.44) ALDH1A1LTA4HTLR8CYP1A2CYP2C9
SCHEMBL6238419 0.87 JAK2 (0.33) ALDH1A1LMNAMAPTHPGDMAPK1
SCHEMBL4943659 0.86 LTA4H (0.44) ALDH1A1LTA4HTLR8KMT2AMEN1
SCHEMBL659359 0.86 LTA4H (0.44) ALDH1A1LTA4HTLR8KMT2AMEN1
SCHEMBL2871187 0.86 LTA4H (0.44) ALDH1A1LTA4HTLR8KMT2AMEN1
SCHEMBL5495328 0.86 LTA4H (0.44) ALDH1A1LTA4HTLR8KMT2AMEN1
SCHEMBL5144146 0.86 LTA4H (0.44) ALDH1A1LTA4HTLR8KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2227 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117969703-A Method for detecting content of thionafil derivative in food or Chinese patent medicine 上海市食品药品检验研究院 2024-05-03 CN claimed
CN-117890459-A Quick screening method for illegally adding chemical drugs into foods based on MSRIT-MS/MS 南京市食品药品监督检验院 2024-04-16 CN claimed
CN-114206886-B Gold (III) compound, method for preparing the same, and organic light emitting device using the same 广东聚华印刷显示技术有限公司 2024-02-27 CN claimed
CN-117229490-A Catalyst composition and application thereof, polylactide and preparation method thereof 中国石油化工股份有限公司 2023-12-15 CN claimed
CN-117229489-A Catalyst composition and application thereof, polylactide and preparation method thereof 中国石油化工股份有限公司 2023-12-15 CN claimed
CN-117126198-A Bidentate phosphine ligand, and preparation method and application thereof 北京旭阳科技有限公司 2023-11-28 CN claimed
CN-117105842-A 3-alkenyl bromo-4-deuterium methyl-pyrrolidine compound, and preparation method and application thereof 河南工学院 2023-11-24 CN claimed
US-20230322816-A1 PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF BEIJING SONGRUN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2023-10-12 US claimed
US-11731954-B2 Histone demethylase inhibitors CELGENE QUANTICEL RES INC (US) 2023-08-22 US claimed
EP-3692088-B1 LATENT CATALYSTS WITH CHELATE LIGANDS FOR POLYMERIZATION OF DICYCLOPENTADIENE (DCPD) UNIV STUTTGART (DE) 2023-08-02 EP claimed
US-4721715-A Derivatives of 4-(arylpiperazinyl-ethylaminoethoxy) phenol useful for effecting hypolipidemic therapy or cardiovascular therapy SOCIETE CORTIAL, S.A. (FR) 1988-01-26 US claimed
EP-0239444-A1 Ferroelectric liquid crystal, process for its manufacture and its use in a liquid-crystal mixture THOMSON-CSF (FR) 1987-09-30 EP claimed
US-4659731-A 2-(4,5-Dihydro-1H-imidazol-2-yl)-2,3-dihydroindole derivatives and their application as α2 receptor antagonist or α1 receptor agonists SYNTHELABO (FR) 1987-04-21 US claimed
EP-0211698-A2 (Dihydro-4,5-1H-imidazolyl-2)-2-dihydro-2,3-indole derivatives, their preparation and their use as medicaments SYNTHELABO (FR) 1987-02-25 EP claimed
US-4604471-A PLASTIC STABILIZERS BASF AKTIENGESELLSCHAFT (DE) 1986-08-05 US claimed
EP-0054132-B1 PYRIMIDONES, THEIR PREPARATION AND MEDICINES CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1984-10-10 EP claimed
US-RE30511-E ENZYME INHIBITOR, HERBICIDE, CYCLIZATION AMERICAN CYANAMID COMPANY (US) 1981-02-10 US claimed
US-4214093-A PROTEOLYTIC ENZYME INHIBITORS TORII & CO., LTD. (JP) 1980-07-22 US claimed
US-4107307-A ENZYME INHIBITORS, HERBICIDES, RING CLOSURE AMERICAN CYANAMID COMPANY (US) 1978-08-15 US claimed
US-3940395-A CNS DEPRESSANT AMERICAN HOME PRODUCTS CORPORATION (US) 1976-02-24 US claimed