Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCND2 | P30279 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17807781 | 0.83 | AURKA (0.40) | AURKACDK1AURKBADORA3ADORA2A | |
| SCHEMBL18898669 | 0.77 | XDH (0.36) | CDK4CCND1CCND2CCND3 | |
| SCHEMBL19421539 | 0.74 | PI4KA (0.34) | AURKACDK1AURKBADORA2AADORA1 | |
| SCHEMBL19200217 | 0.73 | — | — | |
| SCHEMBL29311529 | 0.71 | KDM4E (0.45) | CDK4CCND1CCND2CCND3L3MBTL1 | |
| SCHEMBL31469698 | 0.71 | KMO (0.39) | CDK4CCND1CCND2CCND3L3MBTL1 | |
| SCHEMBL25164705 | 0.70 | HTR2A (0.38) | — | |
| SCHEMBL15970721 | 0.70 | HDAC8 (0.46) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL25164210 | 0.69 | CYP17A1 (0.38) | — | |
| SCHEMBL25164208 | 0.68 | RIPK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663520-B2 | Bicyclic bromodomain inhibitors | ZENITH EPIGENETICS LTD. (CA) | 2017-05-30 | — | — | US | disclosed |