Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 5/20 | 0.38 |
| ▸ | PHGDH | O43175 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18901716 | 0.79 | CCR2 (0.51) | CCR2KCNH2CCR5 | |
| Hydrochloric Acid SCHEMBL3331239 | 0.77 | HRH3 (0.52) | CCR2KCNH2CCR5DRD2DRD3 | |
| SCHEMBL18901699 | 0.74 | HRH3 (0.49) | CCR2KCNH2CCR5DRD2DRD3 | |
| SCHEMBL3025447 | 0.72 | CCR2 (0.78) | CCR2KCNH2CCR5 | |
| SCHEMBL18901441 | 0.72 | CCR2 (0.55) | CCR2KCNH2CCR5 | |
| SCHEMBL18901623 | 0.72 | CCR2 (0.55) | CCR2KCNH2CCR5 | |
| SCHEMBL3324318 | 0.70 | CCR2 (0.63) | CCR2KCNH2CCR5 | |
| SCHEMBL13335025 | 0.70 | CCR2 (0.63) | CCR2KCNH2CCR5 | |
| SCHEMBL3326356 | 0.69 | CCR2 (0.82) | CCR2KCNH2CCR5 | |
| SCHEMBL18901708 | 0.69 | CCR2 (0.57) | CCR2KCNH2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |